| 摘要: |
| ［摘要］ 目的 探讨盐酸利托君联合阿托西班（依宝）治疗早产患者的临床效果。方法 选取2013-01～2015-01该院收治的早产患者80例作为研究对象，根据治疗方法的不同分为对照组和观察组，每组40例。对照组给予盐酸利托君治疗，观察组在对照组的基础上给予阿托西班治疗，对比分析两组患者的治疗效果及不良反应发生情况。结果 观察组宫缩抑制疗效明显优于对照组（P<0.01）；观察组不良反应发生率为15.0%，低于对照组的42.5%，差异有统计学意义（P<0.01）；观察组宫缩消失时间、妊娠延长时间、新生儿体重优于对照组，差异均有统计学意义（P<0.05）；观察组和对照组婴儿存活率分别为97.5%和90.0%，差异无统计学意义（P>0.05）。结论 盐酸利托君联合阿托西班治疗早产患者能够有效抑制宫缩，改善患者临床症状，延长胎儿孕周，对提高胎儿生存质量和存活率具有重要的意义。 |
| 关键词: 早产 盐酸利托君 阿托西班 临床效果 |
| DOI：10.3969/j.issn.1674-3806.2016.06.12 |
| 分类号:R 714.21 |
| 基金项目: |
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| The clinical effect of ritodrine hydrochloride combined with atosiban on patients with premature birth |
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CHEN Chun-yan
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Department of Obstetrics, Maternity and Child Health Hospital of Zhuhai City, Guangdong 519000, China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical effect of ritodrine hydrochloride combined with atosiban in the treatment of premature birth.Methods Eighty patients with premature birth were collected as the research subjects, and divided into the control group and the observation group, with 40 cases in each group, according to the different therapy methods. The control group received ritodrine hydrochloride, and the observation group was administrated atosiban in addition to the routine treatment that was applied to the control group. The clinical effect and the adverse reactions were compared between the two groups.Results The effect of inhibition of uterine contraction in the observation group was significantly better than that in the control group(P<0.01). The incidence of adverse reactions in the observation group（15.0%） was significantly lower than that in the control group（42.5%）, P<0.01. The disappearance time of uterine contraction, pregnancy extension duration and neonatal weight in the observation group were better than those in the control group(P<0.05). There was no significant difference in the survival rate of the infants between the two groups（97.5% vs 90.0%）, P>0.05.Conclusion Ritodrine hydrochloride combined with atosiban can effectively suppress the uterine muscle contractions in patients with premature birth, improve the clinical symptoms, extend the gestational age of fetuses and improve the survival quality of fetuses in patients with premature birth. |
| Key words: Premature birth Ritodrine hydrochloride Atosiban Clinical efficacy |
