| 摘要: |
| ［摘要］ 目的 观察无创正压通气（NIPPV）治疗慢性阻塞性肺疾病(COPD)合并呼吸衰竭患者的临床效果。方法 将收治的102例COPD合并呼吸衰竭患者，随机分为观察组与对照组各51例，对照组给予常规治疗与护理；观察组在常规治疗基础上加用NIPPV，比较两组治疗7 d后的效果。结果 观察组显效18例，有效29例，无效4例;对照组显效13例，有效23例，无效15例，观察组疗效优于对照组(P<0.05)。两组患者的pH值、氧分压（PaO2）、二氧化碳分压（PaCO2）、血氧饱和度（SaO2）、心率、呼吸频率、收缩压、舒张压较治疗前明显改善（P<0.05）,观察组改善程度优于对照组(P<0.05)。结论 采用NIPPV治疗COPD合并呼吸衰竭，能够快速提高通气功能，降低病死率，改善预后，疗效肯定，值得临床推广使用。 |
| 关键词: 慢性阻塞性肺疾病 呼吸衰竭 无创正压通气 临床效果 |
| DOI：10.3969/j.issn.1674-3806.2016.06.16 |
| 分类号:R 563 |
| 基金项目: |
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| Clinical observation of NIPPV in treatment of COPD |
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CHEN Wen-qiang
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Department of Respiratory Medicine, the First People′s Hospital of Qinzhou City, Guangxi 535000, China
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| Abstract: |
| ［Abstract］ Objective To observe the clinical effect of noninvasive positive pressure ventilation(NIPPV) on the patients with respiratory failure and COPD.Methods One hundred and two patients with chronic obstructive pulmonary disease and respiratory failure were divided into the observation group and the control group, with 51 cases in each group. Both of the two groups received conventional treatments and cares and the observation group received additional treatment of NIPPV. The treatment results were compared between the two groups 7 days′ after the treatment.Results In the observation groups, 18 cases had markedly effective results, 29 cases had effective results and 4 cases had no effects. In the control group, 13 cases had markedly effective results 23 cases had effective results and 15 cases had no effects. The curative effect of the observation group was better than that of the control group(P<0.05). pH value, PaO2, PaCO2, SaO2, heart rate, respiratory rate, systolic blood pressure and diastolic blood pressure were improved significantly in both of the two groups after the treatment. However the indicators improved better in the observe group that those in the control group(P<0.05).Conclusion NIPPV can quickly improve the ventilation function, reduce the mortality and improve the prognosis for the patients with copdand respiratory failure. |
| Key words: Chronic obstructive pulmonary disease(COPD) Respiratory failure Noninvasive positive pressure ventilation Clinical effect |
