| 摘要: |
| ［摘要］ 目的 探讨高通量透析对维持性血液透析（MHD）患者钙磷代谢及甲状旁腺激素的影响。方法 选择2013-02～2014-12该院行MHD治疗的62例患者作为研究对象，将患者按随机数字表法分为高通量组32例和低通量组30例，分别给予高通量和低通量血液透析治疗，比较两组透析前及透析后1个月、6个月时血钙、血磷及甲状旁腺激素的水平变化。结果 与透析前相比较，透析后1个月和6个月时高通量组血磷、钙磷乘积、甲状旁腺激素水平均明显下降（P<0.05），而低通量组所有指标均未出现明显变化（P>0.05）。与低通量组比较，透析后1个月、6个月时高通量组血磷、钙磷乘积、甲状旁腺激素水平均明显较低（P<0.05）。结论 高通量血液透析能有效降低MHD患者甲状旁腺激素的水平及改善磷代谢紊乱。 |
| 关键词: 维持性血液透析 高通量 低通量 血磷 血钙 甲状旁腺激素 |
| DOI：10.3969/j.issn.1674-3806.2016.10.14 |
| 分类号:R 582 |
| 基金项目: |
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| The effects of high-flux hemodialysis on calcium phosphorus metabolism and parathyroid hormone in patients with maintenance hemodialysis |
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SU Xiao-xia, LI Hong-bo
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Department of Nephrology, the Second People′s Hospital of Qinzhou, Guangxi 535000, China
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| Abstract: |
| ［Abstract］ Objective To investigate the effects of high-flux hemodialysis on calcium phosphorus metabolism and parathyroid hormone in patients with maintenance hemodialysis(MHD).Methods Sixty-two patients receiving MHD from February 2013 to December 2014 in our hospital were randomly divided into two groups. The high-flux hemodialysis(HFHD) group(n=32) was treated with high-flux hemodialysis, and the low-flux hemodialysis(LFHG) group(n=30) was treated with conventional hemodialysis. The levels of serum calcium, serum phosphorus and parathyroid hormone were compared between the two groups before and 1, 6 months after hemodialysis.Results Compared with those before hemodialysis, the levels of serum phosphorus, calcium-phosphorus product and parathyroid hormone in the HFHD group were significantly decreased 1, 6 months after hemodialysis(P<0.05), however there were no significant differences in the above indicators(P>0.05). Compared with the LFHD group, the levels of serum phosphorus, calcium-phosphorus and parathyroid hormone in the HFHD group were significantly decreased 1, 6 months after hemodialysis(P<0.05).Conclusion High-flux hemodialysis can effectively reduce the levels of serum parathyroid hormone and improve phosphorus metabolism in MHD patients. |
| Key words: Maintenance hemodialysis（MHD） High-flux hemodialysis Low-flux hemodialysis Serum phosphorus Serum calcium Parathyroid hormone |
