| 摘要: |
| ［摘要］ 目的 探讨动脉粥样硬化伴斑块形成的相关危险因素。方法 随机选取2013-12～2014-12到该院体检的300例体检者，根据颈动脉内膜-中层厚度（IMT）和斑块的形态分为颈动脉粥样硬化伴斑块形成组（斑块组）194例和颈动脉粥样硬化无斑块形成组（无斑块组）106例。每例患者均记录患者的性别、年龄、吸烟指数、饮酒指数、体重指数（BMI）、血压（SBP）、空腹血糖（FBG）、总胆固醇（TC）、低密度脂蛋白（LDL）、脂蛋白a［LP(a)］、血尿酸（UA）、同型半胱氨酸（Hcy）等，以及有无高血压、糖尿病病史，应用SPSS17.0软件对斑块组和非斑块组进行单因素分析及Logistic回归分析，比较其可干预的危险因素（排除性别、年龄、遗传等不可干预的因素）与颈动脉粥样硬化的关联程度。结果 两组SBP、FBG、TC、LDL、LP(a)差异有统计学意义（P均<0.05）；其中影响颈动脉粥样硬化因素LDL(OR=9.392)、FBG(OR=2.328)具有统计学意义（P<0.05）。结论 颈动脉粥样硬化是多种危险因素共同作用的结果，其中LDL和FBG是预防动脉硬化优先考虑的独立危险可控制因素。 |
| 关键词: 颈动脉 动脉粥样硬化伴斑块形成 危险因素 低密度脂蛋白 空腹血糖 |
| DOI：10.3969/j.issn.1674-3806.2016.10.20 |
| 分类号:R 54 |
| 基金项目: |
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| The risk factors of the formation of atherosclerosis plaques in carotid artery |
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LUO Song-ping, ZHU Hong, LIN Lei, et al
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Emergency Center, Kaifeng Center Hospital, Henan 475000, China
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| Abstract: |
| ［Abstract］ Objective To explore the risk factors of the formation of atherosclerosis plaques in carotid artery.Methods Three hundred patients were randomly selected from December 2013 to December 2014 for the classification and grading of carotid atherosclerosis. According to the carotid intima-media thickness(IMT) and plaque morphology ,the patients were divided into the plaque group(n=194) and the non plaque group(n=106). The history of high blood pressure, diabetes, age, gender, smoking, alcohol consumption, body mass index(BMI), blood pressure(SBP), fasting blood glucose(FBG), total cholesterol(TC), low density lipoprotein(LDL), lipoprotein a［LP (a)］, blood uric acid(UA) and homocysteine(Hcy) level were recorded in each patient, and Logistic regression analysis was performed by computer with SPSS software to determine the relation between the risk factors and atherosclerosis plaques in the carotid artery.Results There were significant differences in SBP, FBG, TC, LDL and LP(a) between the two groups(P<0.05); There were significant differences in LDL(OR=9.392) and FBG(OR=2.328)(P<0.05) in influencing the carotid atherosclerosis.Conclusion Carotid atherosclerosis is the outcome of mixing actions of many of risk factors,in which LDL and FBG are the independent risk factors. |
| Key words: Carotid artery Atherosclerosis plaques Risk factors Low density lipoprotein Fasting blood glucose |
