| 摘要: |
| ［摘要］ 目的 探讨磷酸肌酸钠在小儿病毒性心肌炎临床治疗中的应用效果。方法 选取2011-01～2015-12收治的92例小儿病毒性心肌炎患者，随机分成两组，每组46例。对照组给予常规方法治疗，治疗组在常规治疗的基础再增加磷酸肌酸钠治疗，观察并比较两组患儿的临床疗效。结果 治疗组显效39例，有效3例，无效4例。对照组显效28例，有效6例，无效12例。治疗组疗效显著优于对照组（P<0.01）。治疗前，两组患儿的CK、CK-MB以及LDH等指标的比较差异无统计学意义（P>0.05）；治疗后，两组患儿的各项心肌酶指标均显著低于治疗前，且治疗组显著优于对照组（P<0.05）。结论 在小儿病毒性心肌炎的临床治疗中合理地应用磷酸肌酸钠，能够有效降低心肌酶，改善心肌功能，提高临床治疗效果，改善患儿预后，值得临床推广应用。 |
| 关键词: 磷酸肌酸钠 病毒性心肌炎 心肌酶 |
| DOI：10.3969/j.issn.1674-3806.2017.07.23 |
| 分类号:R 725.4 |
| 基金项目: |
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| The clinical effect of creatine phosphate sodium on viral myocarditis in children |
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WANG Min-li, SHAN Qiu-ge, ZHANG Li
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Department of Pediatrics, the Second Affiliated Hospital of Luohe Medical College, Henan 462000, China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical effect of creatine phosphate sodium on viral myocarditis in children.Methods Ninety-two children with viral myocarditis in our hospital from January 2011 to 2015 December were randomly divided into two groups, with 46 cases in each group. The control group received conventional therapy and the treatment group received the conventional therapy combined with creatine phosphate sodium. The clinical efficacy was compared between the two groups.Results In the treatment group, the result was markedly effective in 39 cases, effective in 3 cases and invalid in 4 cases. In the control group, the result was markedly effective in 28 cases, effective in 6 cases and invalid in 12 cases. The curative effect of the treatment group was significantly higher than that of the control group(P<0.01). Before the treatment, there were no significant differences in CK, CK-MB and LDH between the two groups(P>0.05); After the treatment, the indicators of myocardial enzymes in the two groups were significantly lower than those before the treatment, and the improvement of the indicators of the treatment group were significantly better than those of the control group(P<0.05).Conclusion Creatine phosphate sodium can effectively reduce myocardial enzymes, improve cardiac function and clinical outcomes in the children with viral myocarditis. |
| Key words: Creatine phosphate sodium Viral myocarditis Myocardial enzymes |
