引用本文:韦红兰,林 忠,樊慧流,吴秀芬,陈武玲,巫晓霞.延长球囊子宫支架放置时间治疗中重度宫腔粘连的疗效及安全性分析[J].中国临床新医学,2020,13(3):262-266.
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延长球囊子宫支架放置时间治疗中重度宫腔粘连的疗效及安全性分析
韦红兰,林 忠,樊慧流,吴秀芬,陈武玲,巫晓霞
545001 广西,柳州市妇幼保健院妇科
摘要:
[摘要] 目的 探讨延长球囊子宫支架放置时间治疗中重度宫腔粘连分离术后预防再次粘连的临床效果及安全性。方法 选择2016-01~2018-12在该院诊断为中重度宫腔粘连并行粘连分离术的患者210例,采用随机数字表法将其分为对照组和观察组,每组105例。对照组在予宫腔镜宫腔粘连分离术后放置球囊子宫支架,1周后整体取出。观察组在予宫腔镜宫腔粘连分离术后放置球囊子宫支架,1周后剪球囊尾管放出球囊内液体,留置球囊支架,术后第2次月经干净后取出。比较两组术后宫腔粘连、月经恢复、并发症的发生情况。结果 对照组术后第1个月月经改善率为72.38%,观察组为77.14%,两组差异无统计学意义(P>0.05);但两组术后第2个月、第3个月及第6个月观察组的月经改善率高于对照组,差异有统计学意义(P<0.05)。对照组宫腔粘连改善有效率为76.19%,观察组为87.62%,差异有统计学意义(P<0.05)。观察组术后并发症发生率高于对照组,差异有统计学意义(9.52% vs 0.00%, χ2=10.500,P=0.001)。结论 延长球囊子宫支架放置时间可以改善宫腔粘连,改善月经量,延长放置球囊子宫支架虽存在一定的风险,但经处理后可治愈,是相对安全的,临床工作中仍需严密观察及随访。
关键词:  球囊子宫支架  延长放置  宫腔粘连  宫腔粘连分离术
DOI:10.3969/j.issn.1674-3806.2020.03.12
分类号:
基金项目:广西卫健委科研课题(编号:Z20170493)
Efficacy and safety of prolonged placement of balloon uterine stent in treatment of moderate to severe intrauterine adhesions
WEI Hong-lan, LIN Zhong, FAN Hui-liu, et al.
Department of Gynaecology, Liuzhou Maternity and Child Healthcare Hospital, Guangxi 545001, China
Abstract:
[Abstract] Objective To explore the clinical efficacy and safety of prolonged placement of balloon uterine stent in prevention of readhension after the separation of moderate to severe intrauterine adhesions. Methods A total of 210 patients diagnosed with moderate to severe intrauterine adhesions and underwent adhesion separation were selected in our hospital from January 2016 to December 2018. The patients were divided into control group and observation group by random number table method, with 105 cases in each group. In the control group, the balloon uterine stent was placed after the separation of intrauterine adhesions by hysteroscopy, and were removed one week later. In the observation group, the balloon uterine stent was placed after the separation of intrauterine adhesions by hysteroscopy, and the tail tube of the balloons was cut to let out the fluid in the balloons one week later, and the stents of the balloons were retained. After the second menstruation, they were removed. The incidence rates of postoperative intrauterine adhesions, menstrual recovery and complications were compared between the two groups. Results The improvement rate of the first menstrual period after operation was 72.38% in the control group and 77.14% in the observation group, but the difference was not statistically significant(P>0.05). However, at the 2nd month, 3rd month and 6th month after operation, the improvement rates of menstruation in the observation group were significantly higher than those in the control group(P<0.05). The effective rate of improvement of intrauterine adhesions was 76.19% in the control group and 87.62% in the observation group, with a significant difference between the two groups(P<0.05). The incidence of postoperative complications in the observation group was higher than that in the control group, and the difference was statistically significant(9.52% vs 0.00%, χ2=10.500, P=0.001). Conclusion Prolonged placement of balloon uterine stent can improve intrauterine adhesion and menstruation. Although prolonged placement of balloon uterine stent has certain risks, the complications caused by the balloon placement can be cured after treatment and is relatively safe. Clinical work still requires close observation and follow-up.
Key words:  Balloon uterine stent  Prolonged placement  Intrauterine adhesions  Hysteroscopic adhesiolysis