| 摘要: |
| ［摘要］ 目的 探讨非体力劳动者和退休人群的维生素D营养状况，并分析其与糖脂代谢的相关性。方法 收集2019年5月至2019年8月在广西壮族自治区人民医院体检中心进行体检的受检者494名数据。均为企事业单位的非体力劳动者和退休人群。分析不同性别、年龄层间维生素D的营养状况差异。比较维生素D正常组和维生素D不足/缺乏组间在体质量指数（BMI）、空腹血糖(FPG)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)的差异情况。分析血清总25-羟维生素D［25-(OH)D］水平与年龄、BMI、血糖和血脂的相关性。结果 494名受检者的血清总25-(OH)D的中位水平为71.68（56.37，87.44)nmol/L；其中维生素D正常者211名（42.71%），不足/缺乏者共283例（57.29%）。男性血清总25-(OH)D水平高于女性，且维生素D营养状况为正常者的人数比例更高，差异有统计学意义（P<0.05）。18～45岁组、46～60岁组和>60岁组血清总25-(OH)D的中位水平分别为64.17（50.85，80.29）nmol/L、73.58（57.15，85.89）nmol/L和77.83（63.45，98.02）nmol/L,维生素D营养状况正常率分别为31.44%、46.67%和54.07%，差异均有统计学意义（P<0.05）。维生素D正常组与不足/缺乏组在BMI、FPG、TC、TG、HDL、LDL方面比较差异均无统计学意义（P>0.05）。血清总25-(OH)D水平与年龄呈正相关（r=0.266，P=0.000），但与BMI、FPG、TC、TG、HDL、LDL相关性不显著（P>0.05）。结论 非体力劳动者和退休人群中维生素D不足和缺乏检出率高，建议非体力劳动者，尤其是室内办公职业人群、年轻女性要积极采取措施补充维生素D。 |
| 关键词: 25-羟维生素D 非体力劳动者 体检人群 糖脂代谢 |
| DOI：10.3969/j.issn.1674-3806.2021.11.16 |
| 分类号:R 153 |
| 基金项目:广西多学科协作健康管理人才小高地项目（编号：桂组通字【2019】85号-九）；广西卫生健康委科研课题（编号：Z20200648）；广西壮族自治区人民医院青年基金项目（编号：QN2019-19） |
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| Nutritional status of vitamin D in non-manual workers and retirees and its correlation with glucose and lipid metabolism |
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PANG Yu, HUANG Guo-xiu, WU Chao-chun, et al.
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Physical Examination Center, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To explore the nutritional status of vitamin D in non-manual workers and retirees, and to analyze its correlation with glucose and lipid metabolism. Methods The data of 494 subjects who underwent physical examination at the Physical Examination Center of the People′s Hospital of Guangxi Zhuang Autonomous Region from May 2019 to August 2019 were collected. They were all non-manual workers and retirees from enterprises and institutions. The difference in the nutritional status of vitamin D was analyzed between different genders and among different age groups. The differences in body mass index(BMI), fasting plasma glucose(FPG), total cholesterol(TC), triglyceride(TG), high density lipoprotein(HDL) and low density lipoprotein(LDL) were compared between the vitamin D normal group and the vitamin D insufficiency/deficiency group. The correlation between serum total 25-hydroxyvitamin D［25-(OH)D］ level and age, BMI, blood glucose and blood fat was analyzed. Results The median level of serum total 25-(OH)D was 71.68(56.37, 87.44)nmol/L in the 494 subjects, among whom 211 cases(42.71%) had normal vitamin D, and 283 cases(57.29%) had insufficient/deficient vitamin D. The serum total 25-(OH)D level in males was higher than that in females, and the proportion of those with normal nutritional status of vitamin D was higher, the difference was statistically significant(P<0.05). The median levels of serum total 25-(OH)D were 64.17(50.85, 80.29)nmol/L, 73.58(57.15, 85.89)nmol/L and 77.83(63.45, 98.02)nmol/L, and the normal rates of nutritional status of vitamin D were 31.44%, 46.67% and 54.07% in the 18～45 years old group, the 46～60 years old group and the >60 years old group, respectively, and the differences were statistically significant(P<0.05). There were no significant differences in BMI, FPG, TC, TG, HDL and LDL between the vitamin D normal group and the vitamin D insufficiency/deficiency group(P>0.05). The serum total 25-(OH)D level was positively correlated with age(r=0.266, P=0.000), but it was not significantly correlated with BMI, FPG, TC, TG, HDL and LDL(P>0.05). Conclusion The detection rate of vitamin D insufficiency/deficiency is high in non-manual workers and retirees. It is recommended that non-manual workers, especially indoor office workers and young females, take active measures to take vitamin D supplements. |
| Key words: 25-hydroxyvitamin D ［25-(OH) D］ Non-manual workers Physical examination population Glucose and lipid metabolism |
