| 摘要: |
| ［摘要］ 目的 观察胫前静脉入路导管接触性溶栓（CDT）治疗急性下肢深静脉血栓形成（DVT）的临床疗效。方法 选择阜阳市第二人民医院2019年1月至2020年3月拟行胫前静脉入路CDT治疗急性下肢DVT患者43例（发病在1周以内）。比较患者治疗前后健患侧下肢周径差。观察患者治疗后并发症发生情况及临床疗效。结果 经胫前静脉入路置管成功39例（90.70%）。患者术后穿刺部位无出血并发症发生，轻度疼痛5例，麻木不适3例。32例术后随访时间3～12个月，随访期间症状消失，无血栓复发及肺栓塞发生。治疗后，患者健患侧下肢周径差显著减小（P<0.05）；静脉通畅评分为(3.29±0.91)分，较治疗前的(8.47±1.09)分下降，差异有统计学意义（t=19.475，P=0.000）；平均静脉通畅率为（57.24±11.57）%；瓣膜保存率达84.38%（27/32）。结论 胫前静脉入路CDT治疗急性下肢DVT临床疗效好，手术并发症少，值得临床推广应用。 |
| 关键词: 深静脉血栓形成 胫前静脉入路 导管接触性溶栓 |
| DOI：10.3969/j.issn.1674-3806.2021.12.09 |
| 分类号:R 543.6 |
| 基金项目:阜阳市卫生健康委科研立项课题（编号：FY2019-066） |
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| Observation on clinical efficacy of catheter-directed thrombolysis via anterior tibial vein approach in treatment of acute deep venous thrombosis of lower extremities |
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SUN Zhen-yang, RUI Qing-feng
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Department of Vascular Surgery, No.2 People′s Hospital of Fuyang City, Anhui 236015, China
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| Abstract: |
| ［Abstract］ Objective To observe the clinical efficacy of catheter-directed thrombolysis(CDT) via anterior tibial vein approach in treatment of acute deep venous thrombosis(DVT) of lower extremities. Methods Forty-three patients with acute DVT of lower extremities(onset within 1 week) were selected from No.2 People′s Hospital of Fuyang City during January 2019 and March 2020 to receive CDT treatment via anterior tibial vein approach. The difference of lower limb circumference between healthy side and affected side was compared before and after treatment. The complications and clinical efficacy were observed in the patients after treatment. Results Thirty-nine cases(90.70%) were successfully catheterized through the anterior tibial vein approach. There were 5 cases of mild pain, and 3 cases of numbness and discomfort but no cases of bleeding complications at the puncture site after the operation. After the operation, 32 cases were followed up for 3-12 months and their symptoms disappeared during the follow-up period, and there was no recurrence of thrombosis and pulmonary embolism. After treatment, the difference of lower limb circumference between the patients′ healthy side and affected side was significantly reduced(P<0.05). The venous patency scores after treatment［(3.29±0.91)points］ were lower than those before treatment［(8.47±1.09)points］, and the differences were statistically significant(t=19.475, P=0.000). The average venous patency rate was (57.24±11.57)%, and the valve preservation rate reached 84.38%(27/32) after treatment. Conclusion CDT via the anterior tibial vein approach has a good clinical effect on the treatment of acute DVT of lower extremities, and there are few surgical complications, and it is worthy of clinical application. |
| Key words: Deep venous thrombosis(DVT) Anterior tibial vein approach Catheter-directed thrombolysis(CDT) |
