| 摘要: |
| ［摘要］ 子宫内膜异位症（EMS）是妇科常见的激素依赖性疾病，好发于育龄期妇女，临床表现以痛经及不孕为主，合并早期复发性流产(RSA)临床报道较少。EMS的发病机制不详，近年来相关研究结果表明，EMS患者出现早期RSA与异位内膜种植造成的卵巢功能损害、免疫调节紊乱、盆腔解剖结构异常、盆腔炎症反应造成胚胎种植部位及发育异常有关。另外，EMS患者存在前列腺素水平升高、血栓前状态、内分泌紊乱及心理因素也是导致早期RSA的重要原因。该文对EMS合并早期RSA的研究进展作一综述。 |
| 关键词: 子宫内膜异位症 早期复发性流产 发病机制 |
| DOI：10.3969/j.issn.1674-3806.2022.02.21 |
| 分类号:R 714.21 |
| 基金项目:广西卫生健康委科研课题（编号：Z20210473） |
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| Research progress of endometriosis complicated with early recurrent spontaneous abortion |
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JIANG Zhi-feng, ZHAO Ren-feng
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Department of Gynaecology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021,China
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| Abstract: |
| ［Abstract］ Endometriosis(EMS) is a common hormone-dependent disease in gynecology, which often occurs in women of childbearing age. The clinical manifestations of EMS are mainly dysmenorrhea and infertility, and the clinical reports of EMS complicated with early recurrent spontaneous abortion(RSA) are less. The pathogenesis of EMS is still unknown. In recent years, relevant studies have shown that early RSA in patients with EMS is related to ovarian function impairment caused by ectopic endometrial implantation, immunomodulatory disorders, abnormal pelvic anatomical structure, embryo implantation site and development abnormalities caused by pelvic inflammatory reaction. In addition, the elevated prostaglandin levels, prothrombotic state, endocrine disorders and psychological factors in patients with EMS are also important causes for early RSA. In this paper, the research progress of EMS complicated with early RSA is reviewed. |
| Key words: Endometriosis(EMS) Early recurrent spontaneous abortion Pathogenesis |
