| 摘要: |
| ［摘要］ 姿势步态障碍（PIGD）是帕金森病（PD）患者的主要症状之一，然而在疾病早期PIGD常常被忽略，未能及时得到识别及诊治。随着疾病进展，步态异常及障碍表现更为突出，严重者出现冻结步态（FOG），更会增加跌倒、骨折甚至死亡风险，严重困扰PD患者的生活工作。一方面，早期识别步态障碍是PD诊断的关键点，对实现PD早期治疗具有重要的临床意义。另一方面，目前临床针对PD的PIGD治疗方法虽较多，但其临床效果尚不明确，迄今仍缺乏有效的治疗干预手段及方法。该文就PD患者的PIGD评估诊断及治疗现状进展作一综述，为PD患者诊疗提供有价值的参考。 |
| 关键词: 帕金森病 步态障碍 诊断 治疗 |
| DOI：10.3969/j.issn.1674-3806.2022.12.01 |
| 分类号:R 741 |
| 基金项目:国家自然科学基金项目（编号：82071416）；广东省自然科学基金-自由项目（编号：2018A030313649） |
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| Progress in diagnosis and treatment of gait disorder in Parkinson′s disease |
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TANG Hong-yin, LIAO Xiang-lian, ZHANG Rui, et al.
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Department of Neurology, Guangdong Second Provincial General Hospital, Guangzhou 510317, China; Second Clinical Medical College, Southern Medical University, Guangzhou 510515, China
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| Abstract: |
| ［Abstract］ Postural instability and gait disorder dominant(PIGD) is one of the main symptoms in patients with Parkinson′s disease(PD). However, PIGD is often neglected in the early stage of the disease and fails to be recognized and diagnosed in time. With the progression of the disease, gait abnormalities and disorders are more prominent, and freezing of gait(FOG) occurs in severe cases, which increases the risk of falls, fractures and even death and seriously afflicts the life and work of PD patients. On the one hand, identifying gait disorders early is a key point in the diagnosis of PD and has important clinical significance for achieving early treatment of PD. On the other hand, although there are many clinical treatments for PIGD in PD at present, their clinical effects are not clear, and there is still a lack of effective therapeutic intervention means and methods. This paper reviews the progress in the evaluation, diagnosis and current status of treatment of PIGD in PD patients, providing a valuable reference for the diagnosis and treatment of PD patients. |
| Key words: Parkinson′s disease Gait disorder Diagnosis Treatment |
