| 摘要: |
| 食管癌是一种常见且具有较高致死率的恶性肿瘤。传统的治疗方法包括手术切除、放疗和化疗,但其疗效有限且副作用较大。随着免疫治疗的快速发展,越来越多的研究开始探索食管癌放疗联合免疫治疗的潜力。本综述旨在总结目前关于食管癌放疗联合免疫治疗的研究进展。首先,介绍食管癌放疗联合免疫治疗的协同作用机制。其次,回顾已有的临床试验和前瞻性研究,评估了放疗联合免疫治疗在食管癌治疗中的疗效和安全性。最后,讨论目前放疗联合免疫治疗在食管癌治疗中存在的问题和挑战,并提出未来研究的方向和展望。综合这些研究结果发现食管癌放疗联合免疫治疗具有巨大的潜力,但仍需要进一步的研究和临床验证。 |
| 关键词: 食管癌 放射疗法 免疫疗法 免疫检查点抑制剂 |
| DOI： |
| 分类号: |
| 基金项目:基于无创智能免疫分型的晚期NSCLC放疗-免疫治疗方案 优化及应用 |
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| Advances in radiotherapy combined with immunotherapy for esophageal cancer |
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liuqianlin
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Affiliated Suzhou Municipal Hospital, Medical School of Nanjing University
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| Abstract: |
| Abstract: Esophageal cancer (EC) is a common and lethal malignant tumour. Traditional treatments include surgical resection, radiotherapy and chemotherapy, however these treatments have limited efficacy and high side effects. With the rapid development of immunotherapy, more and more studies are beginning to explore the potential of radiotherapy combined with immunotherapy in oesophageal cancer. The aim of this review is to summarize the progressions of current research on radiotherapy combined with immunotherapy in oesophageal cancer. Firstly, the synergistic mechanism of radiotherapy combined with immunotherapy for oesophageal cancer is introduced. Secondly, the efficacy and safety of radiotherapy combined with immunotherapy in the treatment of oesophageal cancer are evaluated by reviewing existing clinical trials and prospective studies. Finally, the current problems and challenges of radiotherapy combined with immunotherapy in oesophageal cancer treatment are discussed, and the directions and prospects for future research are proposed. Taken together, these findings suggest that radiotherapy combined with immunotherapy in esophageal cancer has great potential, but further research and clinical validation to prove this works. |
| Key words: Esophageal cancer Radiotherapy Immunotherapy Immunocheckpoint inhibitors |
