| 引用本文: | 袁晓艺,杜紫菲,何胜兰,吕航,王勇.穴位治疗对子宫内膜异位症影响的网状Meta分析：聚焦中医外治法的疗效评估[J].中国临床新医学,0,():-. |
| Yuan Xiaoyi,Du Zifei,He Shenglan,Lv Hang.穴位治疗对子宫内膜异位症影响的网状Meta分析：聚焦中医外治法的疗效评估[J].中国临床新医学,0,():-. |
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| 穴位治疗对子宫内膜异位症影响的网状Meta分析：聚焦中医外治法的疗效评估 |
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袁晓艺1, 杜紫菲2, 何胜兰3, 吕航4, 王勇4
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1.广州中医药大学附属广州中医医院广州;2.广州医科大学附属中医医院;3.广州中医药大学针灸康复临床医学院;4.广州医科大学附属中医医院 广州
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| 摘要: |
| 目的：系统评估以穴位治疗为核心的中医外治法联合中西医药物治疗子宫内膜异位症(EMT)的综合疗效。方法：通过网状Meta分析，检索截至2023年6月1日的相关随机对照试验（RCTs），涵盖PubMed、The Cochrane Library、EMbase等数据库。纳入标准为EMT患者，干预措施包括常规西药、中药、穴位治疗及其组合。结果：共纳入66项RCTs，涉及5172例患者。结果显示，在血清CA125水平的降低方面，西药联合穴位治疗的效果最为显著，其效果优于单纯使用中药治疗（-10.02,[-18.92,-1.16]）。在抑制PGF2??水平方面，西药联合穴位治疗与单纯中药（150.13,[40.01,251.79]）、单纯西药（196.73,[117.72,278.46]）、单纯穴位治疗（181.69,[92.06,271.36]）、中药联合穴位治疗（141.58,[46.37,228.42]）、以及中药联合西药和穴位治疗（-133.76,[-220.23, -43.79]）相比，均显示出更好的效果。然而，在其他生物标志物如E2、FSH、LH和VAS评分水平的改善上，各治疗组间差异无统计学意义。结论：穴位治疗作为辅助疗法，有效促进了EMT关键指标的改善。 |
| 关键词: 子宫内膜异位症 穴位治疗 CA125 随机对照研究 网状Meta分析 |
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| 基金项目:国家自然科学基金项目（82004450）；广东省中医药管理局项目（20231317）；广东省中医药管理局项目（20241222） |
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| Network Meta-Analysis on the Impact of Acupoint Therapy on Endometriosis: Focusing on the Efficacy Evaluation of Traditional Chinese Medicine External Therapy |
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Yuan Xiaoyi,Du Zifei,He Shenglan,Lv Hang
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The Affiliated TCM Hospital of Guangzhou Medical University,Guangzhou
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| Abstract: |
| Objective: To systematically assess the efficacy of Traditional Chinese Medicine (TCM) external therapy, with a focus on acupoint therapy, in conjunction with pharmacological treatments from both Chinese and Western medicine for managing endometriosis (EMT). Methods: This network meta-analysis searched for relevant randomized controlled trials (RCTs) available up to June 1, 2023, across major databases including PubMed, The Cochrane Library, and EMbase. The inclusion criteria targeted EMT patients undergoing interventions such as conventional Western medication, Chinese herbal medicine, acupoint therapy, and their combinations. Results: The analysis incorporated 66 RCTs, involving a total of 5,172 patients. Findings demonstrated that the combination of Western medication and acupoint therapy significantly reduced serum CA125 levels, showing superiority over the use of Chinese herbal medicine alone (-10.02, [-18.92, -1.16]). Regarding the suppression of PGF2?? levels, the amalgamation of Western medication and acupoint therapy exhibited superior outcomes compared to monotherapy with Chinese herbal medicine (150.13, [40.01, 251.79]), Western medication alone (196.73, [117.72, 278.46]), acupoint therapy alone (181.69, [92.06, 271.36]), a combination of Chinese medicine and acupoint therapy (141.58, [46.37, 228.42]), and a triple combination of Chinese medicine, Western medicine, and acupoint therapy (-133.76, [-220.23, -43.79]). However, no statistically significant differences were observed in the improvement of other biomarkers such as E2, FSH, LH, and VAS scores across different treatment groups. Conclusion: Acupoint therapy, as an adjunctive treatment modality, effectively enhances the improvement of key indicators in EMT. |
| Key words: Endometriosis Acupoint Therapy CA125 Randomized Controlled Trials Network Meta-Analysis |
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