| 摘要: |
| ［摘要］ 目的 探讨“药物自我处置程式”训练对精神分裂症患者治疗依从性、社会功能和生活质量的影响。方法 将66例住院非急性期精神分裂症患者随机分为训练组（n=33）和对照组（n=33）。在抗精神病药物治疗不变的前提下，训练组按照Liberman编写的“药物自我处置程式”进行分组训练8周，8周后两组随访6个月。采用自制的药物依从性评分表、社会功能缺陷量表(ＳＤＳＳ)、生活质量综合评定问卷（GQOLI-74）对两组患者进行评估。结果 8周及随访6个月后训练组治疗依从性、SDSS总分、GQOLI-74总分较对照组显著提高（P<0.01、P<0.05）。同组不同时点比较，训练组8周及随访6个月患者治疗依从性、SDSS总分、GQOLI-74总分等较入组时有显著提高（P<0.01或P<0.05）；两组随访6个月的治疗依从性下降，且与8周时的差异有统计学意义（P<0.01)。相关分析显示，在8周和随访6个月后，患者GQOLI-74总分与SDSS总分、治疗依从性呈负相关，SDSS总分与治疗依从性呈正相关（P<0.01)。结论 “药物自我处置程式”训练能提高患者的治疗依从性，改善其社会功能，提高其生活质量。 |
| 关键词: 精神分裂症 药物自我处置程式 社会功能 生活质量 治疗依从性 |
| DOI：10.3969/j.issn.1674-3806.2009.10.04 |
| 分类号:R 749.3 |
| 基金项目:广西医疗卫生自筹经费课题（合同号：Z2007337） |
|
| Study on medication self-management module for patients with schizophrenia |
|
ZHANG Ling, XIE Yan, HE Fen-lan, et al.
|
|
Department of Clinical Psychology, the Nanning Psychology Hospital, Guangxi 530001, China
|
| Abstract: |
| ［Abstract］ Objective To explore the impact of medication self-management module on treatment compliance, social function and quality of life of patients with schizophrenia. Methods Sixty-six inpatients with schizophrenia in non-acute stage were randomly divided into training group(n=33) and control group(n=33).Both groups received the anti-psychotics therapy. Medication self-management module was only given to the training group for 8 weeks. All patients were followed up for 6 months and were evaluated with self-made drug treatment compliance rating scale, social disability screening schedule(SDSS), generic quality of life inventory-74 (GQOLI-74). Results Treatment compliance, the total scores of SDSS and the total scores of GQOLI-74 of training group were significantly higher than those of control group after 8 weeks and 6 months(P<0.01, P<0.05). Treatment compliance, the total scores of SDSS and the total scores of GQOLI-74 of training group after 8 weeks and 6 months were significantly higher than those of pretraining(P<0.05). Treatment compliance of both groups on 6 months follow up were significantly lower than that of 8 weeks (P<0.01).Correlation analysis confirmed negative relation between the total scores of GQOLI-74 and the total scores of SDSS, treatment compliance, and confirmed positive relation between the total scores of SDSS and treatment compliance on 8 weeks and 6 months（P<0.01).Conclusion Medication self-management module could significantly improve treatment compliance, social function and quality of life of patients with schizophrenia. |
| Key words: Schizophrenia Medication self-management module Social function Quality of life Treatment compliance |
