| 摘要: |
| ［摘要］ 目的 探讨度洛西汀治疗躯体化障碍的疗效。方法 将82例躯体化障碍的患者进行为期6周治疗。采用SCL-90评定疗效，副反应量表（TESS）评定副反应，疗效评定以减分率及有效率为评定指标。结果 口服度洛西汀6周后有效率为84.15%，较2周、4周末显著提高（P<0.01)；治疗前躯体化障碍患者SCL-90总分及各项因子分明显高于国内常模，躯体化、焦虑、抑郁、偏执因子分升高明显，治疗后各因子分较治疗前显著降低（P<0.05)，度洛西汀治疗副反应轻微。结论 度洛西汀对躯体化障碍有较好疗效，而副反应较低。 |
| 关键词: 焦虑 抑郁 度洛西汀 躯体化障碍 |
| DOI：10.3969/j.issn.1674-3806.2011.08.18 |
| 分类号:R 749.2 |
| 基金项目: |
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| Evaluations of curative effects of duloxetine in the treatment of patients with somatization disorder |
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ZHOU Gang-zhu
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Mental Hospital of Xinyang, Henan 464000,China
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| Abstract: |
| ［Abstract］ Objective To study the effect of duloxetine in treatment of patients with somatization disorder. Methods Eighty-two patients with somatization disorder were treated with duloxetine 20～40 mg/d for weeks. The clinical effect and side effects was assessed by SCL-90 and TESS respectively. Results At the end of 6 weeks of treatment, the responsive rate was 84. 7%. All item scores of SCL-90 decreased(P<0. 05) and its side effects were less. Conclusion Duloxetine is effective in the treatment of patients with somatization disorder and its side effects were less. |
| Key words: Anxiety Depression Duloxetine Sometization disorder |
