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口服孟鲁司特干预毛细支气管炎后喘息的效果观察
李锦雁,韦元芳,梁修业,朱冠兰
530100 广西,武鸣县妇幼保健院儿科
摘要:
[摘要] 目的 探讨口服孟鲁司特预防毛细支气管炎后反复喘息的效果。方法 将87例临床治愈出院的毛细支气管炎患儿随机分成干预组(46例)和对照组(41例)。干预组给予孟鲁司特口服,1次/d,4 mg/次,持续3个月;对照组治愈出院后未予任何治疗。随访观察1年两组喘息再发作的情况。结果 干预组再发喘息率明显低于对照组(P<0.01或<0.05)。结论 口服孟鲁司特可预防毛细支气管炎后反复喘息及预防哮喘的发生。
关键词:  毛细支气管炎  喘息  孟鲁司特
DOI:10.3969/j.issn.1674-3806.2013.06.20
分类号:R 725.6
基金项目:
Clinical analysis of oral montelukast in preventing asthma attack after bronchilitis
LI Jin-yan, WEI Yuan-fang, LIANG Xiu-ye, et al.
Department of Pediatrics, Maternal and Children Health Hospital of Wuming County, Guangxi 530100,China
Abstract:
[Abstract] Objective To evaluate the effect of oral montelukast in preventing asthma attack after bronchilitis.Methods Eighty-seven bronchilitis infants were divided randomly into intervention group(n=46) and control group,two groups(n=41) received conventional therapy, and the interventiong group was given oral montelukast(4 mg daily for 3 months) on the basis of above therapy. Infants were followed up for 1 year, the effect on asthma attack 1 year after the treatment were observed and compared.Results The recurrent rates of asthma of the intervention group were lower than that of the control group(P<0.01 or P<0.05). Conclusion The oral montelukast can reduces the recurrences of asthma attacks after bronchilitis, asthma might be prevented.
Key words:  Bronchilitis  Asthma  Montelukast