| 摘要: |
| ［摘要］ 目的 探讨目标性救治措施救治重症手足口病(HFMD)患儿的临床效果。方法 对2012年在该院住院的138例重症手足口病患儿（研究组）采用目标性救治。同时将该院2010年未进行目标性救治（均按国家诊疗规范救治）的152例患儿作为对照组进行回顾性对比分析。结果 研究组的病情加重率低于对照组（P<0.01),但两组的抢救成功率和病死率比较差异无统计学意义（P均>0.05）；研究组的症状消失时间和住院时间均短于对照组（P<0.05或<0.01）；研究组的高血糖和神经系统后遗症发生率均低于对照组（P均<0.01)。结论 目标性救治措施为重症HFMD的救治提供了系统性、可操作性的救治方案，可显著缩短临床症状消失时间和住院时间，降低高血糖和神经系统后遗症的发生率，改善预后。 |
| 关键词: 重症手足口病 目标性救治措施 临床效果 |
| DOI：10.3969/j.issn.1674-3806.2014.03.10 |
| 分类号:R 72 |
| 基金项目: |
|
| Targeted treatment measures for children with severe hand- foot-mouth disease:an analysis of clinical efficacy |
|
LU Ji-fang, WANG Zhao-kang
|
|
Department of Pediatrics, Binyang People′s Hospital，Guangxi 530405，China
|
| Abstract: |
| ［Abstract］ Objective To explore the clinical efficacy of targeted treatment measures for children with severe hand-foot-mouth disease(HFMD).Methods On the basis of the mational standard for diagnosis and treatment of HFMD in the treatment group, 138 children with severe HFMD hospitalized in our hospital in 2012 were treated by targeted treatment measures; in the control group 152 children with severe HFMD were not treated by targeted treatment measures, and the clinical efficacy between two groups were retrospectively compared.Results The disease exacerbation rate in the treatment group was lower than that in the control group(P<0.01), but the rescue success rate and case fatality rate were similar between the two groups(P>0.05);the symptems disappearing time and length of hospital stay and breathing machine utilization rate in the treatment group were shorter than those in the control group(P<0.05 or <0.01); the incidence of complications and sequela in the treatment group were lower than those in the control group(P<0.01).Conclusion Targted treatment measares provide a systematic and operational scheme for treating severe HFMD,can obviously shorten the clisappearing time of clinical symptoms and hospitalizationg time,reduce the incidence of hyperglycemia and the sequela of the nerves system,and improve the prognosis. |
| Key words: Severe hand-foot-mouth disease Targeted treatment measures Clinical efficacy |
