| 摘要: |
| ［摘要］ 目的 探讨超敏C反应蛋白在缺血性脑卒中患者诊治中的价值。方法 选取120例缺血性脑卒中患者为疾病组，根据梗死程度的不同，将其分为轻度梗死47例，中度梗死35例，重度梗死38例；同时选择同期性别、年龄等一般资料近似的120名健康体检者设为对照组。检测所有疾病组患者治疗前后及健康体检者的超敏C反应蛋白，并比较分析检测结果，评价超敏C反应蛋白在缺血性脑卒中诊治中的价值。结果 健康体检者、治疗前轻度梗死者、中度梗死者、重度梗死者的超敏C反应蛋白水平分别为(3.32±0.46)mg/L、(8.87±3.72)mg/L、(18.52±6.33)mg/L、(32.51±11.25)mg/L。缺血性脑卒中患者的超敏C反应蛋白水平明显高于健康体检受试者，且随着脑卒中梗死程度的加重，超敏C反应蛋白水平越高，组间比较差异均具有统计学意义（P<0.05）。治疗结束后患者的超敏C反应蛋白水平基本回复到正常水平。结论 超敏C反应蛋白检测具有灵敏度高且快速的优点，可用于缺血性脑卒中患者的临床诊断及治疗效果评价。 |
| 关键词: 超敏C反应蛋白 缺血性脑卒中 诊断 治疗效果 |
| DOI：10.3969/j.issn.1674-3806.2014.03.14 |
| 分类号:R 743.3 |
| 基金项目: |
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| Value of hs-CRP assay detection in the diagnosis and treatment of ischemic stroke |
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HUANG Xiao-chun
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Department of Clinical Laboratories, the People′s Hospital of Liuzhou, Guangxi 545006, China
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| Abstract: |
| ［Abstract］ Objective To explore the value of high-sensitive C-reactive protein(hs-CRP) in the diagnosis and treatment of ischemic stroke.Methods One hundred and twenty cases of ischemic stroke were selected as the disease group, and according to the different levels of infarction, those cases were divided into mild infarction group(47 cases), moderate infarction group(35 cases), severe infarction group(38 cases); Meanwhile a healthy group was set up correspondingly by selecting 120 healthy cases with their general information, such as gender, age, etc, similar to which of the disease group. hs-CRP was detected in all disease groups before and after treatment and healthy group, and their test results were compared.Results The hs-CRP levels of the healthy group and which of the mild infarctions group, the moderate infarction group, the severe infarction group, before treatment were (3.32±0.46)mg/L,(8.87±3.72)mg/L,(18.52±6.33)mg/L,(32.51±11.25)mg/L, respectively. Evidently the hs-CRP levels of ischemic stroke patients were higher than that of healthy people, further, more severe the infarction was, higher its hs-CRP levels was. The differences of above results between the disease groups and the healthy group were significant in statistics(P<0.05). After treatment, the patients′ hs-CRP levels basically returned to normal level.Conclusion The hs-CRP detection is high sensitive and fast. With that advantages, the method can be used in diagnosis of ischemic stroke and evaluation for its treatment effect. |
| Key words: High-sensitivity C-reactive protein(hs-CRP) Ischemic stroke Diagnosis Therapeutic effect |
