| 摘要: |
| ［摘要］ 目的 探讨新生儿呼吸机相关性肺炎（VAP）感染的危险因素以及病原学分析。方法 回顾分析95例接受机械通气危重新生儿的临床资料。结果 VAP的感染率为36.84%（35/95）。不同胎龄、出生体重和通气持续时间与VAP发生有关（P<0.05或0.01）。病原菌多为革兰阴性杆菌(75.6%)，其中前三位分别为肺炎克雷伯菌（26.8%），大肠埃希菌（22.0%）和鲍氏不动杆菌（12.2%），多为耐药菌。结论 VAP发生率高，应减少和监控危险因素，依据病原学及药敏结果合理用药。 |
| 关键词: 新生儿 呼吸机相关肺炎 高危因素 耐药 |
| DOI：10.3969/j.issn.1674-3806.2014.03.18 |
| 分类号:R 722 |
| 基金项目: |
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| Clinical analysis of neonatal ventilator-associated pneumonia |
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XU Jin
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Department of Pediatrics, the People′s Hospital of Yancheng District, Luohe 462300,China
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| Abstract: |
| ［Abstract］ Objective To study the risk factors and the pathogen of neonatal ventilator-associated pneumonia.Methods A retrospective analysis of clinical data of 95 neonates patients who accepted mechanical ventilation was conducted.Results The infection incidence rate of ventilator-associated pneumonia(VAP) was 36.84%(35/95). Statistical analysis showed that different gestational age, birth weight and ventilation duration were the risk factors associated with the development of VAP(P<0.05 or P<0.01). Main pathogenic bacteria were gram negative bacilli(75.6%), of which the first three kinds were Klebsiella pneumoniae(26.8%), Escherichia coli(22%) and Acinetobacter baumannii(12.2%) and most of them were drug resistant bacteria.Conclusion The incidence rate of VAP in neonates high, the risk factors should been reduced and controled, rational use of drugs is done according to pathogens and drug sensitivity results. |
| Key words: Neonate Ventilator associated pneumonia（VAP） Risk factors Drug resistance |
