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丙酸氟替卡松治疗哮喘预测指数阳性喘息婴幼儿的疗效观察
姚行松,林 萌,李 永,朱 虹
350200 福建,长乐市医院儿科
摘要:
[摘要] 目的 观察丙酸氟替卡松治疗哮喘预测指数阳性喘息婴幼儿的疗效。方法 选择该院儿科门诊及住院诊断为哮喘预测指数阳性的喘息婴幼儿作为研究对象,共100例。按随机号码表法分为研究组50例和对照组50例,两组急性期均接受沙丁胺醇气雾剂吸入治疗。缓解期研究组接受丙酸氟替卡松预防治疗,对照组不接受丙酸氟替卡松治疗干预。对研究组和对照组3个月、6个月、9个月时喘息发生率、急诊/住院率进行比较。在两组患儿5岁时回访,计算两组患儿哮喘诊断率。结果 (1)研究组3个月、6个月、9个月喘息发生率、急诊/住院率分别为22%、12%、4%、6%,对照组分别为30%、20%、18%、24%,两组比较差异有统计学意义。研究组和对照组哮喘诊断率分别为16%和44%,差异有统计学意义。结论 丙酸氟替卡松能明显减轻婴幼儿喘息发作程度,减少喘息发作次数。
关键词:  丙酸氟替卡松  哮喘预测指数阳性  婴幼儿
DOI:10.3969/j.issn.1674-3806.2015.09.18
分类号:R 725.6
基金项目:
The effect of fluticasone propionate on babies with asthma predictive index in positive wheezing symptoms
YAO Xing-song, LIN Meng, LI Yong, et al
Department of Pediatric, the Hospital of Changle City, Fujian 350200, China
Abstract:
[Abstract] Objective To investigate the effect of fluticasone propionate on babies with asthma predictive index(API) in positive wheezing symptoms.Methods 100 babies with predictive index in positive wheezing symptoms were collected and divided into the study group and the control group, with 50 cases in each group. The study group received the treatment of fluticasone propionate and the control group received other intervention. The frequency of wheezing episodes and hospitaladmission rates were compared between the two groups at the end of 3, 6 and 9 months. The asthma diagnosis rate was calculated in the two groups with a follw-up when the patients were 5 years old.Results (1)The frequency of wheezing episodes in emergency / hospitalization rates were(22%, 12%, 4%, 6%) at the end of 3, 6 and 9 months in the study group, and the counterpart of data were(30%, 20%, 18%, 24%) in the control group. There were significant differences between the two groups. The asthma diagnostic rates were 16% and 44% in the study group and the control group, respectively, with a significant difference between the two groups.Conclusion Fluticasone propionate can significantly reduce seizure in children with recurrent wheezing, reduce the severity of wheezing attack degree of infants and reduce the times of acute wheezing attack.
Key words:  Fluticasone propionate  Asthma predictive index in postive  Baby