| 摘要: |
| ［摘要］ 目的 探讨复方阿嗪米特联合盐酸伊托必利治疗老年功能性消化不良的临床疗效及安全性。方法 将92例老年功能性消化不良患者随机分为两组。观察组47例给予复方阿嗪米特肠溶片和盐酸伊托必利片治疗，对照组45例仅给予盐酸伊托必利片治疗。比较两组临床疗效及安全性。结果 观察组治疗2周、4周后腹胀、餐后不适、食欲不振等改善程度均明显优于对照组（P<0.05）；观察组治疗2周、治疗4周总有效率分别为68.1%、89.4%，均明显高于对照组的46.7%、66.7%（P<0.05）。治疗期间两组均未出现明显的不良反应。结论 复方阿嗪米特联合盐酸伊托必利能显著改善老年功能性消化不良的症状，提高临床疗效，且安全性较高。 |
| 关键词: 复方阿嗪米特 盐酸伊托必利 老年人 功能性消化不良 |
| DOI：10.3969/j.issn.1674-3806.2015.12.19 |
| 分类号:R 573 |
| 基金项目: |
|
| The efficacy and safety of compound azintamide plus gastric motor drug in treatment of the elderly with functional dyspepsia |
|
WEI Yu-man
|
|
Department of Health, Hechi Hospital of Traditional Chinese Medicine, Guangxi 547000, China
|
| Abstract: |
| ［Abstract］ Objective To evaluate the efficacy and safety of compound azintamide plus gastric motor drug in the treatment of the elderly with functional dyspepsia(FD).Methods Ninety-two elderly patients with FD were randomly divided into two groups. The observation group(n=47) was treated with compound azintamide and itopride hydrochloride tablets and the control group(n=45) was treated with itopride hydrochloride tablets. The efficacy and safety in the two groups were evaluated.Methods The extent of abdominal distention, indisposition after meals and poor appetite improvement was more significant in the observation group than that in the control group after 2 and 4 weeks of the treatment(P<0.05). The total effective rates after 2 and 4 weeks of the treatment in the observation group were 68.1% and 89.4%, which were significantly higher than those in the control group(46.7% and 66.7%)(P<0.05). There were no obvious adverse reactions in the two groups during the period of the treatment.Conclusion Compound azintamide plus itopride hydrochloride tablets is safe and effective in the treatment of elderly patients with FD. |
| Key words: Compound azintamide Itopride hydrochloride Elder Functional dyspepsia(FD) |
