| 摘要: |
| ［摘要］ 肽基脯氨酰顺反异构酶1(PIN1)在肝癌中异常表达，作为肿瘤催化分子在肝癌的增殖、侵袭、凋亡和血管生成等过程中发挥着重要作用。该文从PIN1的分子结构与功能、PIN1在肝癌中的表达及其在肝癌发生、发展中的作用等几方面进行综述。 |
| 关键词: 肽基脯氨酰顺反异构酶1 肝癌 进展 |
| DOI：10.3969/j.issn.1674-3806.2023.10.24 |
| 分类号:R 735.7 |
| 基金项目: |
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| Research progress of peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 in hepatocellular carcinoma |
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MO Zhu-ning, HUANG Li
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Department of Blood Transfusion, the People′s Hospital of Guangxi Zhuang Autonomous Region(Guangxi Academy of Medical Sciences), Nanning 530021, China
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| Abstract: |
| ［Abstract］ Peptidyl-prolyl cis/trans isomerase never in mitosis A(NIMA)-interacting 1(PIN1) is abnormally expressed in hepatocellular carcinoma, and plays an important role in the proliferation, invasion, apoptosis and angiogenesis of hepatocellular carcinoma as a tumor catalytic molecule. This paper reviews the molecular structure and function of PIN1，the expression of PIN1 in hepatocellular carcinoma and its role in the occurrence and development of hepatocellular carcinoma. |
| Key words: Peptidyl-prolyl cis/trans isomerase never in mitosis A(NIMA)-interacting 1(PIN1) Hepatocellular carcinoma Progress |
