| 摘要: |
| ［摘要］ 目的 分析口腔矫治器治疗不同严重程度阻塞性睡眠呼吸暂停（OSA）的疗效。方法 选择2009年12月至2019年10月广西壮族自治区人民医院口腔正畸科收治的OSA或单纯鼾症患者74例。根据多导睡眠图（PSG）检查结果将其分为轻度OSA组（18例）、中度OSA组（18例）、重度OSA组（21例）和单纯鼾症组（17例），各组均接受下颌前移口腔矫治器治疗。比较四组治疗前后睡眠指标和呼吸指标的变化情况。结果 与治疗前比较，轻度OSA组的N3期占比升高，中度OSA组的觉醒指数（ArI）降低，重度组N1期占比降低，差异均有统计学意义（P<0.05）。与治疗前比较，轻度OSA组呼吸暂停指数（AI）、低通气指数（HI）、呼吸暂停低通气指数（AHI）、最长呼吸暂停时间、最长低通气持续时间均减少，睡眠状态下最低血氧饱和度（LSpO2）上升；中度OSA组AI、HI、AHI、最长呼吸暂停时间均减少，睡眠状态下LSpO2上升；重度OSA组AI、HI、AHI、最长呼吸暂停时间、最长低通气持续时间均减少，睡眠状态下LSpO2、清醒状态下平均血氧饱和度（ASpO2）上升，差异均有统计学意义（P<0.05）。结论 口腔矫治器治疗对轻、中度OSA患者均有改善睡眠的作用。经治疗后，不同严重程度OSA患者的呼吸指标参数均获得改善。 |
| 关键词: 阻塞性睡眠呼吸暂停 口腔矫治器 多导睡眠图 睡眠指标参数 呼吸指标参数 |
| DOI：10.3969/j.issn.1674-3806.2023.11.13 |
| 分类号:R 783 |
| 基金项目:广西医疗卫生适宜技术开发与推广应用项目（编号：S2019088）；广西医疗卫生适宜技术研究与开发项目（编号：S201422-06） |
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| Analysis of therapeutic effects of oral appliances on different severities of obstructive sleep apnea |
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RAO Ming-cong, ZHONG Rong-bing, ZHANG Qiu-ping, et al.
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Obstructive sleep apnea(OSA)；Oral appliance；Polysomnography(PSG)；Sleep parameter；Respiratory parameter
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| Abstract: |
| ［Abstract］ Objective To analyze the effects of oral appliances on the treatment of different severities of obstructive sleep apnea(OSA). Methods Seventy-four patients with OSA or primary snoring who were admitted to the Department of Orthodontics of the People′s Hospital of Guangxi Zhuang Autonomous Region from December 2009 to October 2019 were selected. According to the results of polysomnography(PSG), the patients were divided into mild OSA group(18 cases), moderate OSA group(18 cases), severe OSA group(21 cases) and primary snoring group(17 cases). All the four groups were treated with mandibular advancement oral appliances. The changes of sleep indexes and respiratory indexes before and after treatment were compared among the four groups. Results Compared with those before treatment, the proportion of stage N3 in the mild OSA group was increased, and the arousal index(ArI) in the moderate OSA group was decreased, and the proportion of stage N1 in the severe OSA group was decreased, and the differences were statistically significant(P<0.05). Compared with those before treatment, the apnea index(AI), hypopnea index(HI), apnea hypopnea index(AHI), the longest duration of apnea and the longest duration of hypopnea decreased and the lowest arterial oxygen saturation(LSpO2) during sleep increased in the mild OSA group. The AI, HI, AHI and the longest apnea time decreased and LSpO2 during sleep increased in the moderate OSA group. The AI, HI, AHI and the longest apnea time and the longest duration of hypopnea decreased in the severe OSA group, while the LSpO2 during sleep and average arterial oxygen saturation(ASpO2) in awake state in the severe OSA group increased, and the differences were statistically significant(P<0.05). Conclusion Oral appliance treatment can promote sleep improvement in the patients with mild and moderate OSA. After treatment, the respiratory parameters of the patients with different severities of OSA are improved. |
| Key words: Obstructive sleep apnea(OSA) Oral appliance Polysomnography(PSG) Sleep parameter Respiratory parameter |
