| 摘要: |
| ［摘要］ 目的 观察免组织粉碎器的经尿道1 470 nm波长激光（简称“1470激光”）前列腺小块切除术治疗高危良性前列腺增生（BPH）的疗效。方法 回顾性分析2023年7月至2024年7月广东省人民医院收治的100例高危BPH患者的临床资料。根据手术方式的不同将患者分为观察组（行免组织粉碎器的经尿道1470激光前列腺小块切除术，50例）和对照组（行搭配组织粉碎器的经尿道1470激光前列腺剜除术，50例）。比较两组手术相关指标、术后恢复情况、术前和术后3个月国际前列腺症状评分（IPSS）和生活质量（QOL）评分、术后3个月内并发症发生情况。结果 观察组手术时间短于对照组，术中冲洗液使用量少于对照组，差异有统计学意义（P<0.05），但两组术后第1天血红蛋白下降值比较差异无统计学意义（P>0.05）。两组术后尿管冲洗时间、术后尿管留置时间比较差异无统计学意义（P>0.05）。两组术后3个月IPSS、QOL评分均低于术前，差异有统计学意义（P<0.05），但术前、术后3个月两组IPSS、QOL评分比较差异无统计学意义（P>0.05）。观察组无并发症发生，对照组发生尿道狭窄1例（2.00%），两组并发症发生率比较差异无统计学意义（χ2=0.126，P=0.277）。结论 免组织粉碎器的经尿道1470激光前列腺小块切除术治疗高危BPH疗效确切，安全性好，手术流程简化，有效缩短手术时间。 |
| 关键词: 良性前列腺增生 1 470 nm波长激光 疗效 并发症 |
| DOI：10.3969/j.issn.1674-3806.2025.05.10 |
| 分类号: |
| 基金项目:广东省人民医院（广东省医学科学院）引进人才配套科研经费项目（编号：KY0120240010）；国家自然科学基金项目（编号：82373188） |
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| Observation on therapeutic effect of transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer for treatment of high-risk benign prostatic hyperplasia |
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LI Xiangping1, TAO Yingxu1, DENG Jiwang1, LI Guobang1, ZHONG Ruijuan2, WEN Xingqiao1
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1.Department of Urology, Guangdong Provincial People′s Hospital Affiliated to Southern Medical University(Guangdong Academy of Medical Sciences), Guangzhou 510080, China; 2.Operating Room, Guangdong Provincial People′s Hospital Affiliated to Southern Medical University(Guangdong Academy of Medical Sciences), Guangzhou 510080, China
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| Abstract: |
| ［Abstract］ Objective To observe the therapeutic effect of transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer for treatment of high-risk benign prostatic hyperplasia(BPH). Methods The clinical data of 100 patients with high-risk BPH who were admitted to Guangdong Provincial People′s Hospital from July 2023 to July 2024 were retrospectively analyzed. The patients were divided into observation group(receiving transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer, 50 cases) and control group(receiving transurethral 1 470-nm wavelength laser enucleation of the prostate in collocation with a tissue pulverizer, 50 cases) according to different surgical methods. The surgical-related indicators, postoperative recovery, International Prostate Symptom Scores(IPSS) and quality of life(QOL) scores before surgery and 3 months after surgery, and the incidence of complications within 3 months after surgery were compared between the two groups. Results The operation time in the observation group was shorter than that in the control group, and the amount of intraoperative flushing fluid used in the observation group was less than that used in the control group, with statistically significant differences between the two groups(P<0.05). However, there was no statistically significant difference in the decrease in hemoglobin levels between the two groups on the first day after surgery(P>0.05). There was no statistically significant difference in the postoperative flushing time and indwelling time of the urinary catheter between the two groups(P>0.05). The IPSS and QOL scores in both groups 3 months after surgery were lower than those before surgery, and the differences were statistically significant(P<0.05). However, there were no significant differences in IPSS and QOL scores between the two groups before surgery and 3 months after surgery(P>0.05). No complications occurred in the observation group. One case of urethral stricture occurred in the control group(2.00%). There was no significant difference in the incidence of complications between the two groups(χ2=0.126, P=0.277). Conclusion The transurethral 1 470-nm wavelength laser prostatectomy with small-piece removal without morcellation in a tissue pulverizer is effective and safe in treatment of high-risk BPH, and can simplify the surgical process and effectively shorten the surgical time. |
| Key words: Benign prostatic hyperplasia(BPH) 1 470-nm wavelength laser Therapeutic effect Complication |
