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耳念珠菌感染现状及其单细胞测序研究进展
邓超男1，欧阳可贻2，方芷岚2，郭旭光1
1.广州市老年医院检验医学中心，广州 510550；2.广州医科大学附属第三医院检验科，广州 510150
摘要:
［摘要］　耳念珠菌作为一种新发的多重耐药真菌病原体，自2009年首次在日本被发现以来，已在全球范围内迅速传播，成为公共卫生领域的重要挑战。该文综述了耳念珠菌感染的流行现状、临床特点、防控策略以及单细胞测序技术在相关研究中的应用进展，旨在全面了解耳念珠菌感染的现状及单细胞测序技术为其研究可能带来的新机遇。
关键词:  真菌感染  耳念珠菌  单细胞测序
DOI：10.3969/j.issn.1674-3806.2025.07.05
分类号:R 519.3
基金项目:
Current research status of Candida auris infection and research progress in single-cell sequencing of Candida auris infection
DENG Chaonan1, OUYANG Keyi2, FANG Zhilan2, GUO Xuguang1
1.Center for Laboratory Medicine, Guangzhou Geriatric Hospital, Guangzhou 510550, China; 2.Department of Laboratory Medicine, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China
Abstract:
［Abstract］　Candida auris, as an emerging, multidrug-resistant fungal pathogen, has spread rapidly around the world since it was first identified in Japan in 2009, posing a major challenge in the field of public health. This paper reviews the current prevalence, clinical characteristics, prevention and control strategies of Candida auris infection, as well as the application progress of single-cell sequencing technology in the related research of Candida auris infection, aiming to comprehensively understand the current research status of Candida auris infection and the new opportunities that single-cell sequencing technology may bring to the research on it.
Key words:  Fungal infection  Candida auris  Single-cell sequencing