| 摘要: |
| ［摘要］ 重症肺炎支原体肺炎（SMPP）是常见的儿童社区获得性肺炎。SMPP早期识别、高耐大环内酯类药物肺炎支原体（MRMP）感染和并发症监测值得重视。早期识别SMPP危险因素需结合临床特征、炎症生物学标志物及影像学特征。高MRMP感染流行地区，应及时选用新型四环素类（多西环素/米诺环素）或氟喹诺酮类抢先治疗。未来应加强MRMP监测、优化预警模型，并探索多学科协作的管理策略。 |
| 关键词: 重症肺炎支原体肺炎 耐大环内酯类药物肺炎支原体 诊断 治疗 儿童 |
| DOI：10.3969/j.issn.1674-3806.2025.08.01 |
| 分类号:R 725.6 |
| 基金项目:国家重点研发计划“中医药现代化”重点专题项目（编号：2024YFC3506000） |
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| Focus on diagnosis and treatment of severe Mycoplasma pneumoniae pneumonia in children |
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CUI Yun, JING Xiaoping, ZHANG Yucai
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Department of Critical Care Medicine, Shanghai Children′s Hospital(Shanghai Children′s Hospital, Shanghai Jiao Tong University School of Medicine), Shanghai 200062, China
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| Abstract: |
| ［Abstract］ Severe Mycoplasma pneumoniae pneumonia(SMPP) is a common community-acquired pneumonia in children. The early detection of SMPP, as well as the monitoring of highly macrolide-resistant Mycoplasma pneumoniae(MRMP) infection and complications deserve attention. The early detection of risk factors for SMPP requires a combination of clinical features, inflammatory biological markers and imaging features. In the regions where MRMP infection is highly prevalent, new tetracyclines(doxycycline/minocycline) or quinolones should be promptly selected for early treatment. In the future, efforts should be made to strengthen the monitoring of MRMP, optimize its early warning model, and explore the management strategies involving multidisciplinary collaboration. |
| Key words: Severe Mycoplasma pneumoniae pneumonia(SMPP) Macrolide-resistant Mycoplasma pneumoniae(MRMP) Diagnosis Treatment Children |
