| 摘要: |
| ［摘要］ 目的 分析11例肺炎支原体肺炎（MPP）合并肺动脉栓塞患儿的临床特征及预后。方法 回顾性分析2023年5月至2024年5月内蒙古自治区人民医院收治的11例MPP合并肺动脉栓塞患儿的临床资料及随访结果。结果 11例患儿中男5例，女6例，中位年龄8（5～14）岁。所有患儿均有发热、咳嗽症状，伴胸痛5例，呼吸困难3例，呼吸音减低6例，喘鸣音3例；有胸腔积液5例，纵隔气肿1例。肺部CT血管成像（CTA）示肺动脉部分分支栓塞。所有患儿D-二聚体水平均不同程度升高（1.22～17.07 μg/mL）。11例患儿均使用了大环内酯类抗生素、多西环素以及低分子肝素钙治疗。7例病情得到控制，4例遗留闭塞性细支气管炎。结论 儿童MPP合并肺动脉栓塞多表现为咳嗽、发热、胸痛、呼吸困难，伴有D-二聚体水平不同程度升高，应给予积极抗感染、抗凝及溶栓治疗，多数预后良好。 |
| 关键词: 肺炎支原体肺炎 肺动脉栓塞 儿童 临床特征 预后 |
| DOI：10.3969/j.issn.1674-3806.2025.08.05 |
| 分类号: |
| 基金项目:内蒙古医科大学联合项目（编号：YKD2023LH078）；内蒙古自治区科技计划项目（编号：2021GG0122）；公立医院科研联合基金科技项目（编号：2024GLLH0085） |
|
| Analysis on clinical features of 11 cases of Mycoplasma pneumoniae pneumonia complicated with pulmonary embolism in children |
|
FAN Yuhong, LI Junli, SU Xuewen
|
|
Department of Pediatrics, Inner Mongolia Autonomous Region People′s Hospital, Hohhot 010000, China
|
| Abstract: |
| ［Abstract］ Objective To analyze the clinical features and prognosis of 11 cases of Mycoplasma pneumoniae pneumonia(MPP) complicated with pulmonary embolism in children. Methods A retrospective analysis was conducted on the clinical data and follow-up results of 11 pediatric patients with MPP complicated with pulmonary embolism who were admitted to Inner Mongolia Autonomous Region People′s Hospital from May 2023 to May 2024. Results Among the 11 pediatric patients, there were 5 males and 6 females, with a median age of 8 years(ranging from 5 to 14 years). Fever and cough were found to exist in all the pediatric patients, accompanied by chest pain in 5 patients, difficulty breathing in 3 patients, decreased breath sounds in 6 patients, wheezing in 3 patients, pleural effusion in 5 patients and mediastinal emphysema in 1 patient. Pulmonary computed tomography angiography(CTA) showed partial branch embolism in the pulmonary artery. The levels of D-dimer in all the pediatric patients were increased to varying degrees［(1.22-17.07)μg/mL］. The 11 pediatric patients were treated with macrolide antibiotics, doxycycline and low-molecular-weight heparin calcium. Seven pediatric patients′ conditions were controlled, while 4 pediatric patients had residual bronchiolitis obliterans. Conclusion MPP complicated with pulmonary embolism in children mostly presents with cough, fever, chest pain, and difficulty breathing, accompanied by elevated levels of D-dimer at different levels. Active anti-infection, anticoagulant and thrombolytic treatments should be given to the children, and most of them have a good prognosis. |
| Key words: Mycoplasma pneumoniae pneumonia(MPP) Pulmonary embolism Children Clinical features Prognosis |
