| 摘要: |
| ［摘要］ 目的 观察中频电疗仪经皮穴位刺激联合鼓室内注射甲泼尼龙治疗突发性聋的效果。方法 招募2023年6月至2024年11月安徽医科大学附属宿州医院耳鼻喉科收治的突发性聋患者120例，采用随机数字表法将其分为对照组和观察组，各60例。对照组接受鼓室内注射甲泼尼龙治疗，观察组接受中频电疗仪经皮穴位刺激联合鼓室内注射甲泼尼龙治疗。两组疗程均为4周。比较两组临床疗效、平均听阈值、耳鸣致残量表评分、眩晕评定量表评分、言语识别测试结果、血液流变学指标和不良反应发生情况。结果 观察组临床总有效率高于对照组，差异有统计学意义（95.00% vs 83.33%； χ2=4.227，P=0.040）。在治疗4周后，观察组平均听阈值、耳鸣致残量表评分、眩晕评定量表评分、高切全血黏度、低切全血黏度、血浆黏度、红细胞压积和红细胞聚集指数较对照组更低，言语识别正确率、红细胞变形指数高于对照组，差异有统计学意义（P<0.05）。两组不良反应总发生率比较差异无统计学意义（P>0.05）。结论 中频电疗仪经皮穴位刺激联合鼓室内注射甲泼尼龙治疗突发性聋效果显著，能有效改善听力水平及血液流变学指标，缓解眩晕症状，安全性好。 |
| 关键词: 中频电疗仪 经皮穴位刺激 鼓室内注射 甲泼尼龙 突发性聋 |
| DOI：10.3969/j.issn.1674-3806.2025.08.11 |
| 分类号: |
| 基金项目:宿州市科技计划项目（编号：SZZCZJ202224） |
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| Observation on efficacy of transcutaneous electrical acupoint stimulation using a medium-frequency electrotherapy device combined with intratympanic injection of methylprednisolone for treatment of sudden sensorineural hearing loss |
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ZHANG Yameng1, TIAN Chunhui2, LIU Hongfeng1
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1.Department of Pharmacy, Suzhou Hospital of Anhui Medical University(Suzhou Municipal Hospital), Suzhou 235200, China; 2.Department of Otolaryngology, Suzhou Hospital of Anhui Medical University(Suzhou Municipal Hospital), Suzhou 235200, China
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| Abstract: |
| ［Abstract］ Objective To observe the efficacy of transcutaneous electrical acupoint stimulation(TEAS) using a medium-frequency electrotherapy device combined with intratympanic injection of methylprednisolone for treatment of sudden sensorineural hearing loss(SSNHL). Methods A total of 120 patients with SSNHL who were admitted to Department of Otolaryngology, Suzhou Hospital of Anhui Medical University from June 2023 to November 2024 were recruited. The patients were divided into control group and observation group by using random number table method, with 60 patients in each group. The control group received intratympanic injection of methylprednisolone for treatment, while the observation group received TEAS using a medium-frequency electrotherapy device combined with intratympanic injection of methylprednisolone for treatment. The treatment courses in both groups were 4 weeks. The clinical efficacy, average hearing threshold, Tinnitus Disability Scale scores, Vertigo Rating Scale scores, results of speech-recognition test, hemorheological indicators and occurrence of adverse reactions were compared between the two groups. Results The total clinical effective rate of the observation group was significantly higher than that of the control group, with statistically significant difference between the two groups(95.00% vs 83.33%; χ2=4.227, P=0.040). After 4 weeks of treatment, the average hearing threshold, Tinnitus Disability Scale scores, Vertigo Rating Scale scores, high-shear whole blood viscosity, low-shear whole blood viscosity, plasma viscosity, hematocrit and erythrocyte aggregation index in the observation group were lower than those in the control group, and the correct rate of speech recognition and erythrocyte deformation index in the observation group were higher than those in the control group, with statistically significant differences between the two groups(P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05). Conclusion TEAS using a medium-frequency electrotherapy device combined with intratympanic injection of methylprednisolone is significantly effective in treatment of SSNHL. It can effectively improve the hearing level and hemorheological indicators, relieve vertigo symptoms, and has good safety. |
| Key words: Medium-frequency electrotherapy device Transcutaneous electrical acupoint stimulation(TEAS) Intratympanic injection Methylprednisolone Sudden sensorineural hearing loss(SSNHL) |
