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广西成年居民血脂异常流行现状及影响因素分析
毛 玮1,罗水英1*,邓惠天2,唐美艳3,蒋小云1,黄金梅1,许晶晶1,滕有明1,钟延旭1,4
1.广西壮族自治区疾病预防控制中心慢性非传染性疾病防制所,南宁 530028;2.广西医科大学公共卫生学院,南宁 530021;3.右江民族医学院公共卫生学院,百色 533000;4.广西壮族自治区疾病预防控制中心广西病毒性肝炎防治重点实验室,南宁 530028
摘要:
[摘要] 目的 了解2023年广西成年居民血脂异常的流行现状及影响因素,为制订防控策略提供科学依据。方法 2023年12月至2024年2月,采用多阶段分层整群随机抽样方法,选取广西18岁及以上常住居民6 231名,开展问卷调查、体格检查和实验室检测。使用R 4.4.2软件进行χ2检验及多因素logistic回归分析。结果 本研究共纳入6 099名调查对象进行分析,其中血脂异常2 787例,血脂异常率为45.70%,标化血脂异常率为45.97%。其中高总胆固醇血症、高甘油三酯血症、低高密度脂蛋白胆固醇血症和高低密度脂蛋白胆固醇血症的标化患病率分别为21.25%、16.17%、22.37%和14.75%。多因素logistic回归分析结果显示,45~59岁和≥60岁、农村居民、每天吸烟、超重和肥胖、高血压、糖尿病是促进血脂异常发生的危险因素(P<0.05),女性是抑制血脂异常发生的保护因素(P<0.05)。结论 2023年广西成人血脂异常率较高,应重点针对男性、45岁以上、农村、吸烟、超重和肥胖及慢性病人群,采取生活方式干预以控制危险因素,降低患病风险。
关键词:  血脂异常  流行病学  影响因素  广西
DOI:10.3969/j.issn.1674-3806.2026.04.13
分类号:R 589.2
基金项目:广西医疗卫生适宜技术开发与推广应用项目(编号:S2021066);广西壮族自治区疾病预防控制中心青年博士提升科研能力课题(编号:[2025]第3988号)
Analysis on the prevalence and influencing factors of dyslipidemia among adult residents in Guangxi
MAO Wei1, LUO Shuiying1*, DENG Huitian2, TANG Meiyan3, JIANG Xiaoyun1, HUANG Jinmei1, XU Jingjing1, TENG Youming1, ZHONG Yanxu1,4
1.Institute of Chronic Non-Communicable Disease Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China; 2.School of Public Health, Guangxi Medical University, Nanning 530021, China; 3.School of Public Health, Youjiang Medical University for Nationalities, Baise 533000, China; 4.Guangxi Key Laboratory for Viral Hepatitis Prevention and Treatment, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China
Abstract:
[Abstract] Objective To understand the prevalence and influencing factors of dyslipidemia among adult residents in Guangxi in 2023, and to provide a scientific basis for formulating prevention and control strategies. Methods From December 2023 to February 2024, a multi-stage stratified cluster random sampling method was used to select 6 231 permanent residents aged 18 years and above in Guangxi. Questionnaire surveys, physical examinations and laboratory tests were conducted on the selected permanent residents. Chi-square test and multivariate logistic regression analysis were performed on the collected data using R 4.4.2 software. Results A total of 6 099 respondents were included in this study for analysis, among whom 2 787 respondents had dyslipidemia, with a prevalence rate of dyslipidemia of 45.70%. The age-standardized prevalence rate of dyslipidemia was 45.97%, and the age-standardized prevalence rates of hypercholesterolemia, hypertriglyceridemia, hypo-high-density lipoprotein cholesterolemia and hyper-low-density lipoprotein cholesterolemia were 21.25%, 16.17%, 22.37% and 14.75%, respectively. The results of multivariate logistic regression analysis showed that age range of 45-59 years and ≥60 years, rural residents, daily smoking, overweight and obesity, hypertension and diabetes were risk factors for promoting the occurrence of dyslipidemia(P<0.05), while female was a protective factor for inhibiting the occurrence of dyslipidemia(P<0.05). Conclusion In 2023, the prevalence rate of dyslipidemia among adults in Guangxi is relatively high. Lifestyle interventions should be focused on males, people over 45 years old, rural residents, smokers, overweight and obese individuals, and people with chronic diseases to control risk factors and reduce the risk of illness.
Key words:  Dyslipidemia  Epidemiology  Influencing factors  Guangxi

*并列第一作者