| 摘要: |
| ［摘要］ 目的 探讨超短波联合血流限制抗阻训练（BFR-RT）对膝关节骨性关节炎（KOA）患者疼痛、关节功能、平衡能力及炎症水平的改善效果与临床应用价值。方法 招募2024年2月至12月就诊于解放军总医院第一医学中心的92例Kellgren-Lawrence分级Ⅱ～Ⅲ级KOA患者作为研究对象。采用随机数字表法将患者分为观察组和对照组，每组46例。对照组采用常规康复训练，观察组采用超短波联合30%一次最大负荷量BFR-RT，干预周期均为8周。比较两组干预前、干预4周后、干预8周后的视觉模拟量表（VAS）评分、西安大略和麦克马斯特大学骨关节炎指数（WOMAC）评分、Berg平衡量表评分。分别于干预前、干预8周后检测血清白细胞介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）水平。结果 两组干预后VAS评分、WOMAC评分呈下降趋势（P<0.05），且在干预4周后、干预8周后，观察组低于对照组，差异有统计学意义（P<0.05）。两组干预后Berg平衡量表评分呈上升趋势（P<0.05），且在干预4周后、干预8周后，观察组高于对照组，差异有统计学意义（P<0.05）。干预8周后，两组IL-6、TNF-α水平较干预前降低，且观察组低于对照组，差异有统计学意义（P<0.05）。干预期间，两组均未出现严重不良事件。结论 超短波联合BFR-RT可快速缓解KOA患者疼痛，减轻局部炎症，显著改善关节功能与平衡能力，安全性高，可为Kellgren-Lawrence分级Ⅱ～Ⅲ级KOA的非手术治疗提供优化方案。 |
| 关键词: 膝关节骨性关节炎 超短波 血流限制抗阻训练 疼痛管理 关节功能康复 |
| DOI：10.3969/j.issn.1674-3806.2026.09.08 |
| 分类号:R 684 |
| 基金项目:国家重点研发计划项目（编号：2023YFC2412004） |
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| Clinical efficacy of ultrashort wave combined with blood flow restriction resistance training in treatment of knee osteoarthritis |
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Liu Yuanyuan1,Wang Gang2,Tian Yuling3
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1.Outpatient Department, Haidian 20th Retirement Cadre Rest Home, Beijing 100195,China; 2.Department of Rehabilitation Medicine, the First Medical Centre, Chinese PLA General Hospital, Beijing 100039, China; 3.Department of Rehabilitation, Beijing Nuclear Industry Hospital, Beijing 100045, China
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| Abstract: |
| ［Abstract］ Objective To investigate the clinical efficacy and application value of ultrashort wave combined with blood flow restriction resistance training(BFR-RT) in relieving pain, improving joint function and balance ability, and reducing inflammatory levels in patients with knee osteoarthritis(KOA). Methods A total of 92 patients with Kellgren-Lawrence grade Ⅱ-Ⅲ KOA who were admitted to the First Medical Centre of Chinese PLA General Hospital from February 2024 to December 2024 were enrolled as study subjects. The patients were divided into observation group and control group by random number table method, with 46 patients in each group. The control group received conventional rehabilitation training, while the observation group received ultrashort wave combined with BFR-RT at 30% one-repetition maximum(1RM). The intervention period was 8 weeks for both groups. Visual Analogue Scale(VAS) scores, Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) scores and Berg Balance Scale(BBS) scores were compared between the two groups before intervention, 4 weeks after intervention, and 8 weeks after intervention. Serum levels of interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) were measured before intervention and at 8 weeks post-intervention. Results After intervention, the VAS scores and WOMAC scores in both groups showed a downward trend(P<0.05). Moreover, the VAS scores and WOMAC scores in the observation group were lower than those in the control group 4 weeks and 8 weeks after intervention, with statistically significant differences(P<0.05). After intervention, the BBS scores in both groups showed an upward trend(P<0.05), and the BBS scores in the observation group were higher than those in the control group 4 weeks and 8 weeks after intervention, with statistically significant differences(P<0.05). At 8 weeks post-intervention, the levels of IL-6 and TNF-α in both groups were lower than those before intervention, and the IL-6 and TNF-α levels in the observation group were lower than those in the control group after intervention, with statistically significant differences(P<0.05). During the intervention period, no severe adverse events occurred in either group. Conclusion Ultrashort wave combined with BFR-RT is safe and effective in rapidly relieving pain, reducing local inflammation, significantly improving joint function and balance ability in KOA patients. The combination can provide an optimized therapeutic regime for non-surgical treatment of Kellgren-Lawrence grade Ⅱ-Ⅲ KOA. |
| Key words: knee osteoarthritis(KOA) ultrashort wave blood flow restriction resistance training(BFR-RT) pain management joint function rehabilitation |
