| 摘要: |
| ［摘要］ 目的 探讨血液透析滤过（HDF）和间歇性血液透析（IHD）治疗老年慢性肾功能衰竭的疗效、透析相关并发症发生率及对患者营养状况的影响。方法 将45例老年慢性肾功能衰竭患者随机分为治疗组（HDF组）23例，对照组（IHD组）22例，检测两组患者治疗前后血清尿素氮（Bun）、肌酐（Scr）、血红蛋白、血清白蛋白；观察皮脂肌肉消耗情况及胸腹水发生率；计算尿素氮清除率（kt/V）；并对比两组病人并发症的发生情况。结果 治疗组病人kt/V>1.2，对照组病人kt/V<1.2，两组透析充分性比较有统计学意义(P<0.05)。治疗组病人的血红蛋白、血清白蛋白水平显著高于对照组病人；治疗组病人皮脂肌肉消耗不明显；治疗组胸腹水发生率明显低于对照组(P<0.05)。结论 血液透析滤过能显著提高患者生活质量，为老年肾功能衰竭患者提供了一个更安全、更高效的治疗模式。 |
| 关键词: 血液透析滤过 间歇性血液透析 老年慢性肾功能衰竭 |
| DOI： |
| 分类号:R 692.5 |
| 基金项目: |
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| Clinical observation of senile patients with chronic renal failure treated with hemodiafiltration therapy |
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WU Qiu-xia, GONG Zhi-feng, PENG Xiao-mei, et al.
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Kidney Dep.the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To investigate the therapeutic effect of hemodiafiltration (HDF) and intermittent hemodialysis(IHD)on senile patients with chronic renal failure, the incidence of dislysis correlative syndrome, and the effect on the nutritional status.Methods Forty-five cases were divided in to two groups: 23 cases with hemodiafiltration therapy (group HDF), and 22 patients treated with intermittent hemodialysis (group IHD). The levels of urea nitrogen (Bun), serum creatinine (Scr), hemoglobin and serum albumin were detected; the loss of sebum cutaneum and skeletal muscle, the incidence of pleural fluid and hydroperitoneum were observed; the values of urea nitrogen clearance (kt/V) were calculated; and the incidence of complication in each group was compared in all cases before and after treatment.Results kt/V>12 in HDF group while kt/V<12 in IHD group. The differences of dialysis adequacy between the two groups were significant (P<0.05). The levels of hemoglobin and serum albumin in HDF group were significantly higher than those in group IHD. There was no obvious loss of sebum cutaneum and skeletal muscle in group HDF. There was low incidence of pleural fluid and ascites in group HDF.Conclusion Hemodiafiltration can obviously improve the quality of life of patients, and it is a better way for treating chronic renal failure. |
| Key words: Hemodiafiltration Intermittent hemodialysis Chronic renal failure |
