引用本文:陈祺棠.阿奇霉素治疗儿童社区获得性细菌性肺炎临床观察[J].中国临床新医学,2009,2(6):621-623.
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阿奇霉素治疗儿童社区获得性细菌性肺炎临床观察
陈祺棠
535000 广西,钦州市一医院儿科
摘要:
[摘要] 目的 观察阿奇霉素治疗轻、中度儿童社区获得性细菌性肺炎的疗效和安全性。方法 74例社区获得性肺炎患儿随机分为两组,治疗组34例口服阿奇霉素每日5 mg/kg,1次/d;连续5~7 d;对照组40例予阿莫西林/克拉维酸30 mg/kg静脉滴注,2次/d,连续应用5~7 d。结果 治疗组总有效率为85.3%,对照组总有效率80.0%,两组总有效率比较差异无统计学意义(χ2=0.36,P>0.05)。结论 阿奇霉素是治疗社区获得性细菌性肺炎安全、有效的药物。
关键词:  阿奇霉素  社区获得性细菌性肺炎
DOI:10.3969/j.issn.1674-3806.2009.06.28
分类号:R 725.6
基金项目:
Azithromycin in treament of children with community-acquired bacterial pneumonia
CHEN Qi-tang
Department of Pediatrics, the First People′s Hospital, Qinzhou 535000, China
Abstract:
[Abstract] Objective To investigate the efficacy and safety of azithromyci in treatment of children with mild and middle community-acquired bacterial pneumonia.Methods Seventy-four patients were randomly divided into the treatment group and the control group.The patients of the treatment group(n=34) received the treatment with oral azithromycin in a dose of 5mg/kg, one time daily for 5~7days;the patients of the control group (n=40) received the treatment with intravenous drip of augmentin in a dose of 30mg/kg, two time daily for 5~7 days.Results A satisfactory clinical response (the cured plus the improved)was achieved at the rate of 85.3% and 80.0% repectively in the treatment with azithromycin and augmentin(χ2=0.36, P>0.05).Conclusion These results indicate that azithromycin is effective and safe in the treatment of children with mild and middle community-acquired bacterial pneumonia.
Key words:  Azithromycin  Community-acquired bacterial pneumonia