| 摘要: |
| ［摘要］ 目的 探讨胃癌化疗所致的高度致呕的有效治疗方法。方法 将84例胃癌患者随机分成实验组（42例）与对照组（42例），两组患者均采用相同的化疗方案（ECF方案）。在化疗过程中对于发作性、突发性呕吐实验组联用甲氧氯普胺、地西泮，对照组加用格拉司琼，观察两组治疗前后的止呕率、依从性及住院时间等指标变化情况。结果 对照组治疗急性、突发性恶心的有效率为54.1%，防治呕吐的有效率为71.4%；实验组的分别为85.7%和92.9%，两组比较差异有统计学显著意义(P<0.05)。结论 甲氧氯普胺、地西泮及格拉司琼联用于肿瘤化疗所致的急性、突发性恶心呕吐能达到止吐率明显增加、依从性好及住院时间缩短的效果，且经济、高效，安全性高。 |
| 关键词: 胃癌化疗 高度致呕性 急性，突发性恶心 |
| DOI：10.3969/j.issn.1674-3806.2010.03.24 |
| 分类号:R 587.1 |
| 基金项目: |
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| Observation on prevention and treatment effect of chemotherapy induced highly vomiting in 84 patients with gastric cancer |
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ZHANG Ji-jun,WEI Song,WEI Ai-fang
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Hechi People′s Hospital,Guangxi 547000,China
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| Abstract: |
| ［Abstract］ Objective To discuss the effective method of treatment for chemotherapy induced highly vomiting in patients with gastric cancer.Methods Eighty-four patients with gastric cancer were randomly divided into the experimental group (n=42 ) and the control group (n=42).Two group received the same chemotherapy plan ECF.During chemotherapy,the treatment methods for acute and sudden vomiting were:the experimental group was given the metoclopramide and diazepamum;the control group was given granisetron. The controlling vomiting rate, hospital time and the compliance were observed in two groups.Results The effective controlling rate for acute and sudden nausea was 54.1%, the effective controlling rate for vomiting was 71.4% in the control group,and 85.7%,92.9% in the experimental group,respectively,there was significant statistic difference in curative effects between two group(P<0.05).Conclusion The combined application of metoclopramide, diazepamum and granisetron in chemotherapy induced acute and sudden nausea and vomiting, can obviously increase the controlling vomiting rate, with good the compliance and less hospital time. Also it is an economic, highly effective and safe method. |
| Key words: Chemotherapy for gastric cancer Highly induced vomiting nature Acute, Sudden nausea |
