| 摘要: |
| ［摘要］ 目的 分析颈围与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的相关性，研究颈围对预测该病的价值并寻找最佳筛查值。方法 以2009-06～2012-06因睡眠打鼾、高血压、糖尿病要求了解睡眠状况，在我中心行多导睡眠图（PSG）检测的≥18岁患者为对象，PSG检测前进行颈围、腰围等指标的测量。以PSG为金标准监测，分析颈围与呼吸暂停低通气指数(AHI)值之间的关系，并利用ROC曲线分析颈围对OSAHS的诊断价值，从中选择出最佳敏感度与特异度的颈围值。结果 符合研究条件的受检者2 167例，年龄18～89(45.0±14.34)岁,颈围21.0～58.0(38.17±3.567)cm。男性颈围大于女性颈围［（39.13±3.029)cm vs (34.07±2.683)cm，P=0.001］。轻、中、重度OSAHS患者之间颈围差异有统计学意义［（37.86±3.474）cm vs （38.24±2.935）cm vs (39.87±3.043）cm，P=0.000］。AHI与颈围呈正相关(r=0.109，P=0.000)。以PSG-AHI≥5、10、15次/h为金标准制作颈围筛查ROC曲线，显示PSG-AHI15次/h为金标准时ROC曲线下面积最大。男性颈围≥39.25 cm时，敏感度为50.0%，特异度为52.5%；女性颈围≥34.75 cm时，敏感度为75.5%，特异度为58.6%。结论 颈围与OSAHS的AHI呈正相关，颈围在一定程度上可以作为筛查OSAHS的指标，男性颈围≥39.25 cm时，女性颈围≥34.75 cm时，可以预测中重度OSAHS。 |
| 关键词: 颈围 阻塞性睡眠呼吸暂停低通气综合征 筛查 |
| DOI：10.3969/j.issn.1674-3806.2012.11.09 |
| 分类号:R 56 |
| 基金项目:广西自然科学基金资助项目(编号：桂科自0991211) |
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| Research of neck circumference in preliminary diagnosis of obstructive sleep apnea hypopnea syndrome |
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SONG Wei,JIANG Li-jun,LIU Jian-hong,et al.
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Guangxi Sleep Respiratory Disease Diagnosis and Treatment Center,the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021,China
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| Abstract: |
| ［Abstract］ Objective To analyze the correlation of neck circumference(NC)and obstructive sleep apnea hypopnea syndrome(OSAHS), to research the value of NC in diagnosis of OSAHS and find the best diagnosis score.Methods From June 2009 to June 2012, a set of adult patients with snoring, arousal induced by breathing domination, or patients with hypertension and diabetes mellitus who intend to know the sleep status, were selected from the Sleep Disordered Breathing Center of the People′s Hospital of Guangxi Zhuang Autonomous Region. The age range of the sample was more than 18 years. The polysomnography(PSG) were undertaken in all patients. Before the PSG the height, weight, neck circumference, waist, hip circumference and so on were measured. The relationship of NC and OSAHS-AHI was analyzed, the ROC curve was used to research the value of NC in diagnosis of OSAHS, from which choosing NC score that had the best sensitivity and specificity.Results Two thousand, one hundred and sixty-seven subjects meeting the research requirements had the complete research date. The mean age of them was (45.0±14.34)years, the age range was from 18 to 89 years, the mean NC was (38.17±3.567)cm. The female NC was significantly lower than the male ［（39.13±3.029）cm vs (34.07±2.683)cm, P=0.000］. Mild, moderate, and severe OSAHS patients′ NC were different ［（37.86±3.474)cm vs (38.24±2.935)cm vs (39.87±3.043)cm, P=0.000］. AHI and NC had correlation (r=0.109,P=0.000).PSG-AHI was used as The Gold Standard for making the ROC curve, when AHI≥15 was used as The Gold Standard the acreage under the ROC curve was maximum. When male NC ≥39.25 cm, sensitivity was 50.0%,specificity was 52.5%;female NC ≥34.75 cm, sensitivity was 75.5%,specificity was 58.6%.Conclusion AHI and NC has correlation, to a certain extent, NC can be used to diagnose OSAHS, when male NC ≥39.25 cm,sensitivity was 50.0%,specificity was 52.5%;female NC ≥34.75 cm, sensitivity was 75.5%,specificity was 58.6%,it can to predict moderate or severe OSAHS. |
| Key words: Neck circumference Obstructive sleep apnea hypopnea syndrome Preliminary diagnosis |
