| 摘要: |
| ［摘要］ 目的 探讨甲氨蝶呤(MTX)+垂体后叶素用于腹腔镜保守治疗输卵管妊娠的临床效果。方法 对未破裂型输卵管妊娠采取腹腔镜开窗取胚+局部注射MTX保守手术治疗患者148例,按术中是否联合使用垂体后叶素分观察组和对照组各74例。观察组应用MTX+垂体后叶素在妊娠输卵管病灶基底部系膜内注射治疗;对照组单用MTX注射治疗。观察两组术中出血量、手术时间、输卵管病灶需电凝止血例数、术后血HCG水平及持续性异位妊娠发生率等情况。结果 观察组术中出血量和需电凝止血例数明显减少、手术时间明显缩短，两组比较差异有统计学意义(P均<0.01)；两组术后血HCG水平、持续性异位妊娠发生率比较差异无统计学意义(P>0.05)。结论 腹腔镜异位妊娠开窗手术中应用MTX+垂体后叶素治疗效果明显，能有效减少电凝止血对输卵管组织的损伤，降低持续性异位妊娠的发生率。 |
| 关键词: 输卵管妊娠 腹腔镜 甲氨蝶呤 垂体后叶素 治疗 |
| DOI：10.3969/j.issn.1674-3806.2013.07.15 |
| 分类号:R 714 |
| 基金项目: |
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| Clinical efficacy of laparoscopic conservative operation in the treatment of tubal pregnancy:Report of 148 cases |
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QIN Yan-fen,WU Li-ying,QIN Hua-chan
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Department of Obstetrics and Gynecology,the First People’s Hospitol of Hechi City,Guangxi 546300,China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical efficacy of methotrexate (MTX) combined with pituitrin in the laparoscopic treatment of tubal pregnancy.Methods One hundred and forty-eight patients with unbroken tubal pregnancy were treated by laparsocopic fendstration and embryo-taken surgery plus local injection of MTX. The patients were divided into two groups according to whether using pituitrin or not. Observation group(n=74) received injection of MTX combind with pituitrin into the pregnancy tubal; Control group(n=74) received injection of MTX only. The conditions of two groups were observed including bleeding volume, operation time, pregnancy tubal electrocoagulation times, postoperatied blood,HCG level, persistent ectopic pregnancy(PEP) rate, etc.Results Observation group had less bleeding volume, less operation time, less electrocoagulation times than control group. There were significant differences between two group(P<0.01); While the conditions of postoperative serum HCG level and PEP rate between two groups had no statistical significance(P>0.05).Conclusion Applying MTX combined with pituitrin in the laparoscopic fenestration opration for ectopic pregnancy has obvious therapeutical effect which can lessen the electrocoagulation injury to tubal tissue and the incidence of PEP effectively. |
| Key words: Tubal pregnancy Laparoscopes Methotrexate(MTX) Pituitrin Treatment |
