| 摘要: |
| ［摘要］ 慢性阻塞性肺疾病（COPD）常并发呼吸衰竭，机械通气是重要治疗措施，其中无创通气(NIV)是临床上常用治疗方法。NIV治疗COPD急性加重期急性呼吸衰竭可以改善患者的呼吸功能、动脉血氧饱和度和降低通气插管率。NIV治疗COPD稳定期慢性呼吸衰竭也能改善动脉血氧饱和度、生活质量和运动耐力。严重酸中毒、高血糖和患者病情严重等是预测NIV治疗失败因素。该文对NIV治疗COPD急性加重期和稳定期、NIV参数设置、影响NIV疗效因素方面进行了综述。 |
| 关键词: 慢性阻塞性肺疾病 呼吸衰竭 机械通气 |
| DOI：10.3969/j.issn.1674-3806.2013.09.29 |
| 分类号:R 56 |
| 基金项目:广西卫生厅科研课题（编号：桂卫Z2006143）；广西科技厅攻关项目（编号：桂科攻0816004-9） |
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| Research progress on the non-invasive ventilation for the treatment of respiratory failure in chronic obstructive pulmonary disease |
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QIN Zhi-qiang, TAN Yi
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Department of Respiratory Disease, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Respiratory failure is common in chronic obstructive pulmonary disease (COPD) and usually needs ventilation, which includes non-invasive ventilation (NIV). Clinical studies have confirmed that the NIV can benifit the respiratory function, improve the parameters of arterial blood gas analysis and reduce the endotracheal intubation rate in the patients with acute respiratory failure in actue exacerbation of COPD. NIV can also improve the parameters of artierial blood gas analysis, quality of life and excercise tolerance of patients with chronic respiratory failure in stable COPD. Severe acidosis, hyperglycaemia and more severe conditions are the predict factors of poor NIV outcome. This paper reviews the research progress on the non-invasire ventilation for the treatment of respiratory failure in chronic obstructive pulmonary disease. |
| Key words: Chronic obstructive pulmonary disease（COPD） Respiratory failure Mechanical ventilation |
