| 摘要: |
| ［摘要］ 目的 研究肺部混合磨玻璃结节影（mixed ground-glass opacity,mGGO)的疾病构成、诊断技术及疾病与影像学特点关系。方法 前瞻性研究经病理证实的19例连续性肺部mGGO病例的基本临床资料、影像学特征（包括病灶大小、边缘特征、GGO百分比、内部特征、邻近特征、结节外表现）。根据确诊结果分为良性病变组和恶性病变组，并比较上述观察指标。结果 19例肺部mGGO结节中良性病变4例（良性病变组），恶性15例（恶性病变组）。恶性病变组中CT表现分叶征（86.7%）、边界清楚（86.7%）和血管集束征（80.0%）明显高于良性病变组。恶性病变组GGO百分比≤50%为14例，良性病变组仅1例（P=0.016）。基本临床资料、病灶大小、部位、内部特征、结节外表现及结节至壁层胸膜距离在良恶性病变组中均无差异（P均>0.05）。11例CT引导经皮穿刺肺活检均获确诊。结论 肺部mGGO结节的CT表现对病变性质鉴别诊断有一定意义。经皮穿刺肺活检术对肺部mGGO结节确诊率高。 |
| 关键词: 肺结节影 计算机断层扫描 诊断技术 |
| DOI：10.3969/j.issn.1674-3806.2014.03.06 |
| 分类号:R 56；R 445 |
| 基金项目:广西卫生厅科研课题（编号：Z2013332） |
|
| Clinical analysis of 19 consecutive cases of pulmonary mixed ground-glass opacity nodules |
|
JIANG Ling-yu, QIN Zhi-qiang, WANG Yi, et al.
|
|
Department of Respiratory Disease, the People′s Hospital of Guangxi Zhuang Autonomous Region，Nanning 530021, China
|
| Abstract: |
| ［Abstract］ Objective To investigate the proportion and diagnostic techniques of pulmonary mixed ground-glass opacity(mGGO), and the relationship between the disease and computed tomography(CT) characteristics.Methods Single mGGO were found in 22 consecutive patients which underwent multi-detector CT. Nineteen(86.4%) consecutive cases of mGGO nodules that were histologically confirmed were included in this prospective trial. All cases of pulmonary mGGO nodules were divided into two groups: malignant nodules group and benign nodules group. The clinical and radiological characteristics(including the lesions′ size, edge characteristics, internal characteristics, etc) of all patients were recorded. These parameters were statistically compared between the two groups.Results There were 4 benign and 15 malignant mGGOs. No statistical differences were found between benign and malignant mGGOs in terms of demographic data, lesions′ size, internal characteristics and external manifestations. The frequency of lobulation(86.7%), well-defined interface（86.7%） and vascular convergence（80.0%）was significantly higher in malignant mGGOs than that in benign mGGOs. The percentage of GGO component ≤50% was higher in malignant mGGOs. The diagnostic of 11 cases were confirmed through percutaneous core needle lung biopsy under multi-CT fluoroscopic guidance.Conclusion The CT characteristics of pulmonary mGGO nodules have certain significance in the differential diagnosis of lesions properties of pulmonary mGGO nodules. CT fluoroscopy-guided needle aspiration biopsy is a useful diagnostic technique for mGGO nodules. |
| Key words: Pulmonary nodules Computed tomography Diagnostic techniques |
