| 摘要: |
| ［摘要］ 目的 探讨冠心病患者血脂异常及炎症反应与颈动脉斑块形成的关系。方法 选择2009-05～2013-04在该院住院治疗的132例冠心病患者，彩超检查颈动脉显示伴有颈动脉斑块形成93例（观察组），不伴有颈动脉斑块39例（对照组）。均常规检测总胆固醇（TC）、低密度胆固醇（LDL-C）、甘油三酯（TG）、高密度胆固醇（HDL-C）和超敏C反应蛋白(hs-CRP)。结果 观察组血清TC和LDL-C均高于对照组（P<0.05或<0.01），而两组的hs-CRP、TG及HDL-C差异无统计学意义（P均>0.05）。结论 冠心病患者中高TC和高LDL-C可能与颈动脉斑块形成有关，而hs-CRP与颈动脉斑块形成无明显关联。 |
| 关键词: 冠心病 颈动脉斑块 血脂异常 超敏C反应蛋白（hs-CRP） 相关性 |
| DOI：10.3969/j.issn.1674-3806.2014.03.07 |
| 分类号:R 54 |
| 基金项目:北海巿科学研究与技术开发计划项目（编号：北科合20110901） |
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| The relationship between abnormal blood lipid and inflammatory reaction and carotid atherosclerotic plaque formation in patients with coronary heart disease |
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LU Zhi-dong, PAN Qing-deng, HUANG Yong-kang
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Department of Internal Medicine, the Second People′s Hospital of Beihai，Guangxi 536000，China
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| Abstract: |
| ［Abstract］ Objective To investigate whether or not the abnormal blood lipid and inflammatory reaction associated with carotid atherosclerotic plaque formation in patients with coronary heart disease.Methods One hundred and thirty-two coronary heart disease patients with or without carotid atherosclerotic plaque hospitalized in our hospital from May 2009 to April 2013 were enrolled in this study, including 93 patients with carotid atherosclerotic plaque(observation group) and 39 patients without carotid atherosclerotic plaque(control group). Total cholesterol（TC）, low density lipoprotein cholesterol（LDL-C）, triglyceride（TG）, high density lipoprote cholesterol（HDL-C） and hypersensitive C-reactive protein(hs-CRP) in all patients were detected routinely.Results The observation group had higher TC and higher LDL-C than the control group（P<0.05 and P<0.01, respectively）. However，TG, HDL-C and hs-CRP between two groups had not statistically significant difference（P all >0.05）.Conclusion In patients with coronary heart disease, higher TC and higher LDL-C may be related with the formation of carotid plaque，while hs-CRP has not apparently related with the formation of carotid plaque. |
| Key words: Coronary heart diseas Carotid atherosclerotic plaque Abnormal blood lipid Hypersensitive C-reactive protein(hs-CRP) Relationship |
