| 摘要: |
| ［摘要］ 目的 观察采用阿奇霉素、头孢哌酮/舒巴坦联合小剂量地塞米松治疗大叶性肺炎的效果。方法 选择大叶性肺炎患者172例，按照随机数字表法分为对照组和观察组各86例。对照组给予阿奇霉素联合小剂量地塞米松治疗，观察组给予阿奇霉素、头孢哌酮/舒巴坦联合小剂量地塞米松治疗，比较两组患者的临床疗效和不良反应的发生率。结果 观察组疗效明显优于对照组(95.35% vs 86.05%，P<0.05)。治疗过程中，过敏性皮疹、过敏性休克、寒颤、呼吸急促等不良反应发生率对照组为9.30%，观察组为16.28%，两组比较差异无统计学意义(P>0.05)。结论 采用阿奇霉素、头孢哌酮/舒巴坦联合小剂量地塞米松治疗大叶性肺炎患者临床效果较为显著，不良反应少，值得临床推广使用。 |
| 关键词: 阿奇霉素 头孢哌酮/舒巴坦 地塞米松 大叶性肺炎 临床疗效 |
| DOI：10.3969/j.issn.1674-3806.2015.09.20 |
| 分类号:R 563.1 |
| 基金项目: |
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| Clinical effect of the triple therapy on lobar pneumonia |
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GAO Li-min
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Department of Respiratory,Zhengzhou City Children′s Hospital, Henan 450000, China
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| Abstract: |
| ［Abstract］ Objective To explore the effect of the joint use of azithromycin, cefoperazone/sulbactam and dexamethasone on patients with lobar pneumonia.Methods 172 patients with lobar pneumonia were collected and divided into the control group and the observation group by the random number table method, with 86 cases in each group. The patients of the control group were given azithromycin combination with a small dose of dexamethasone treatment. The patients of the observation group were given azithromycin, cefoperazone/sulbactam in combination with a small dose of dexamethasone treatment. The clinical curative effects and adverse reactions were compared between the two groups.Results The total effective rate was elevated in the observation group than that in the control group(95.35 % vs 86.05%, P<0.05). The incidence of adverse reactions such as allergic skin rashes, anaphylactic shock, chills and shortness of breath was 9.30% in the observation group, and 16.28% in the control group, with no significant difference(P>0.05).Conclusion The combination use of azithromycin, cefoperazone/sulbactam and a small dose of dexamethasone in the treatment of lobar pneumonia is effective and safe. |
| Key words: Azithromycin Cefoperazone/sulbactam Dexamethasone Lobar pneumonia Clinical curative effect |
