引用本文:薛 莲,薛素清,李苑红.改良腹腔镜保守手术联合米非司酮治疗输卵管妊娠的效果观察[J].中国临床新医学,2016,9(3):195-197.
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改良腹腔镜保守手术联合米非司酮治疗输卵管妊娠的效果观察
薛 莲,薛素清,李苑红
514400 广东,五华县中医医院妇产科(薛 莲,李苑红);514400 广东,五华县妇幼保健院妇产科(薛素清)
摘要:
[摘要] 目的 探讨改良腹腔镜保守手术联合米非司酮治疗输卵管妊娠的疗效。方法 随机选取该院2013-04~2015-03收治的输卵管妊娠患者96例,随机分为两组。研究组给予改良腹腔镜保守手术联合米非司酮进行治疗;对照组采用一般腹腔镜保守手术进行治疗,对比分析两组患者的手术时间、术中出血量、住院天数、术后血HCG下降率及患侧输卵管的通畅度。结果 (1)研究组患者的手术时间、术中出血量及住院天数均明显低于对照组,差异具有统计学意义(P<0.05)。(2)研究组患者的术后血HCG 2周的转阴率高于对照组,且差异具有统计学意义(P<0.05)。(3)研究组患者的术后输卵管阻塞例数少于对照组,但差异无统计学意义(P>0.05)。结论 采用改良腹腔镜保守手术联合米非司酮治疗输卵管妊娠,可以有效预防持续性异位妊娠的发生,在最大限度上保留了输卵管的完整性和功能性,值得临床推广应用。
关键词:  改良腹腔镜保守手术  米非司酮  输卵管妊娠  临床应用
DOI:10.3969/j.issn.1674-3806.2016.03.03
分类号:R 714
基金项目:广东省梅州市科技局科研立项课题(编号:2013B94)
Improved conservative laparoscopic surgery combined with medication of mifepristone in the treatment of tubal pregnancy
XUE Lian, XUE Su-qing, LI Yuan-hong
Department of Obstetrics and Gynecology, the Chinese Medicine Hospital of Wuhua County, Guangdong 514400, China
Abstract:
[Abstract] Objective To explore the efficacy of laparoscopic conservative surgery combined with medication of mifepristione in the treatment of unruptured tubal pregnancy.Methods A total of 96 cases with tubal pregnancy in our hospital from April 2013 to March 2015, were randomly divided into two groups. The study group(n=48) was treated with modified laparoscopic conservative surgery combined with medication of mifepristone. The control group was treated with conservative laparoscopic surgery. The operative time, blood loss, hospital stay, blood HCG and the patency of oviduct were compared between the two groups.Results (1)The operative time, hospitalization days and blood loss of the study group were significantly shorter or less than those of the control group(P<0.05). (2)The postoperative blood HCG drop rate and the negative conversion rate of blood HCG 2 weeks after the surgery were higher in the study group than those in the control group(P<0.05). (3)There were no significant difference in the postoperative tubal obstruction between the study group and the control group(P>0.05).Conclusion Modified laparoscopic surgery combined with medication of mifepristone is effective in preventing the occurrence of persistent ectopic pregnancy, and retains the integrity and function of the ociduct to the greatest extent.
Key words:  Modified laparoscopic conservative surgery  Mifepristone  Tubal pregnancy  Clinical application