引用本文:刘桂良,梁珍花,王 敏,朱瑞凯,黄翰武,张 健,石 磊,陈升鑫,陈祥荣,丘国政,吕立文.儿童暴发性心肌炎的临床特点及体外膜肺氧合救治效果分析[J].中国临床新医学,2021,14(5):441-445.
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儿童暴发性心肌炎的临床特点及体外膜肺氧合救治效果分析
刘桂良,梁珍花,王 敏,朱瑞凯,黄翰武,张 健,石 磊,陈升鑫,陈祥荣,丘国政,吕立文
530021 南宁,广西壮族自治区人民医院儿科
摘要:
[摘要] 目的 分析儿童暴发性心肌炎的临床特点和体外膜肺氧合(ECMO)的救治效果。方法 回顾性分析2018-07~2020-12该院收治的8例儿童暴发性心肌炎的临床特点和ECMO的救治效果。结果 8例暴发性心肌炎患儿中,5例接受了心肺复苏,4例出现多器官功能障碍综合征。ECMO支持时间91 h(20~190 h),ECMO撤机成功7例,出院存活6例,存活患儿神经功能正常,心功能均恢复良好。发生并发症3例,其中1例出现严重神经系统并发症,最终脑死亡。结论 儿童暴发性心肌炎常以心外症状就诊,容易出现恶性心律失常,ECMO救治儿童暴发性心肌炎效果良好。
关键词:  儿童  暴发性心肌炎  体外膜肺氧合
DOI:10.3969/j.issn.1674-3806.2021.05.04
分类号:R 725.4;R 654.1
基金项目:广西卫健委科研课题(编号:Z20170357);广西医疗卫生适宜技术开发与推广应用项目(编号:S2018065);南宁市青秀区科技计划项目(编号:2019035)
Analysis of the clinical characteristics of fulminant myocarditis in children and the therapeutic effect of extracorporeal membrane oxygenation
LIU Gui-liang, LIANG Zhen-hua, Wang Min, et al.
Department of Pediatrics, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
Abstract:
[Abstract] Objective To analyze the clinical characteristics of fulminant myocarditis in children and the therapeutic effect of extracorporeal membrane oxygenation(ECMO). Methods A retrospective analysis was conducted on the clinical characteristics of fulminant myocarditis in 8 children treated in the People′s Hospital of Guangxi Zhuang Autonomous Region from July 2018 to December 2020 and the therapeutic effect of ECMO. Results Of the 8 children with fulminant myocarditis, 5 received cardiopulmonary resuscitation and 4 developed multiple organ dysfunction syndrome. The ECMO support time was 91 hours(20-190 hours), and 7 cases were successfully weaned from ECMO, and 6 cases survived to hospital discharge. The neurological function of the surviving children was normal and their cardiac function recovered well. Complications occurred in 3 cases. Among the children with complications, 1 case had severe neurological complications and eventually died of brain death. Conclusion Children with fulminant myocarditis often seek medical treatment because of extracardial symptoms, and are prone to malignant arrhythmia. ECMO is effective in treatment of fulminant myocarditis in children.
Key words:  Children  Fulminant myocarditis  Extracorporeal membrane oxygenation(ECMO)