引用本文:尹文娟,苏 丹,谭蔚泓.淋巴上皮瘤样癌分子病理研究进展[J].中国临床新医学,2021,14(9):845-851.
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淋巴上皮瘤样癌分子病理研究进展
尹文娟,苏 丹,谭蔚泓
310022 杭州,中国科学院大学附属肿瘤医院(浙江省肿瘤医院)病理科(尹文娟,苏 丹);中国科学院大学附属肿瘤医院(谭蔚泓);中国科学院基础医学与肿瘤研究所(尹文娟,苏 丹,谭蔚泓)
摘要:
[摘要] 淋巴上皮瘤样癌(LELC)是一组少见的与病毒感染密切相关的上皮性恶性肿瘤,可发生于全身任何器官。由于发病率低,LELC大样本临床研究缺乏,其发生的病因、发病机制、临床病理及分子病理特点尚不明确。该文就上述几方面进行文献综述,以期能够更好地了解LELC的发病及分子病理特征。
关键词:  淋巴上皮瘤样癌  病因  发病机制  分子病理特征
DOI:10.3969/j.issn.1674-3806.2021.09.02
分类号:R 73
基金项目:
Progress in molecular pathology of lymphoepithelioma-like carcinoma
YIN Wen-juan, SU Dan, TAN Wei-hong
Department of Pathology, Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital); Institute of Basic Medicine and Cancer(IBMC), Chinese Academy of Sciences, Hangzhou 310022, China
Abstract:
[Abstract] Lymphoepithelioma-like carcinoma(LELC) is a group of rare epithelial malignant tumors closely related to viral infection, which may occur in any organ of the body.Due to its low incidence, large scale clinical trials of LELC are lacking. The etiology, pathogenesis, clinicopathological and molecular pathological features of LELC are still unclear. This paper reviews the literature on the above aspects to better understand the pathogenesis and molecular pathological features of LELC.
Key words:  Lymphoepithelioma-like carcinoma(LELC)  Etiology  Pathogenesis  Molecular pathological feature