| 摘要: |
| ［摘要］ 子宫内膜异位症（ES）是临床上常见的女性疾病，表现为盆腔疼痛、不孕症或附件包块等。ES一直被认为是发生ES相关性卵巢癌（EAOC）的潜在危险因素，主要包括子宫内膜样和透明细胞两种类型，是上皮性卵巢癌的亚组。目前，EAOC的危险因素和发病机制仍不完全明确。该文对EAOC发病机制及靶向治疗的研究进展作一综述。 |
| 关键词: 子宫内膜异位症相关性卵巢癌 分子生物学 遗传学 治疗 |
| DOI：10.3969/j.issn.1674-3806.2021.11.21 |
| 分类号:R 737 |
| 基金项目:甘肃自然科学基金项目（编号：20JR5RA151） |
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| Research progress in the pathogenesis and targeted therapy of endometriosis-associated ovarian cancer |
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ZHAO Jing, ZHANG Qin, LIU Jian, et al.
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The First Clinical Medical College of Gansu University of Chinese Medicine(Gansu Provincial Hospital), Lanzhou 730000, China
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| Abstract: |
| ［Abstract］ Endometriosis(ES), manifested as pelvic pain, infertility or adnexa mass, is a clinically common female disease. ES has always been considered as a potential risk factor for the development of endometriosis-associated ovarian cancer(EAOC), and EAOC is a subgroup of epithelial ovarian cancer(EOC), mainly including endometriosis-like and clear cell types. At present, the risk factors and pathogenesis of EAOC are still not completely clear. This paper reviews the research progress in the pathogenesis and targeted therapy of EAOC. |
| Key words: Endometriosis-associated ovarian cancer(EAOC) Molecular biology Genetics Therapy |
