| 摘要: |
| ［摘要］ 手术切除是肝内胆管细胞癌首选的治疗方法，也是唯一可能的治愈手段。R0切除是影响肝内胆管细胞癌手术预后的重要因素，在保证R0切除和手术安全性的基础上，切缘距离应>10 mm。淋巴结是否转移是肝内胆管细胞癌手术最重要的预后因素之一，淋巴结清扫能改善患者的预后，术后辅以系统治疗可以延长患者的生存期。对于起始不可切除的肝内胆管细胞癌患者，辅助化疗是一个可能获得根治性手术切除机会的有效措施。 |
| 关键词: 肝内胆管细胞癌 手术切除 淋巴结清扫 |
| DOI：10.3969/j.issn.1674-3806.2022.02.02 |
| 分类号:R 735.7 |
| 基金项目:山东省自然科学基金项目（编号：ZR2017LH007） |
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| Progress in surgical treatment of intrahepatic cholangiocarcinoma |
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ZHANG Zhi-hao, LIU Feng
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Department of Hepatobiliary Surgery,the First Affiliated Hospital of Shandong First Medical University(Shandong Provincial Qianfoshan Hospital), Jinan 250014, China
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| Abstract: |
| ［Abstract］ Surgical resection is the preferred treatment and the only possible cure for intrahepatic cholangiocarcinoma(ICC). R0 resection is an important factor affecting the surgical prognosis of ICC. On the basis of ensuring R0 resection and the surgical safety, the resection margin should be greater than 10 mm. Whether lymph node metastasis exists is one of the most important prognostic factors of surgery for ICC. Lymphadenectomy can improve the prognosis of the patients, and adjuvant postoperative systemic therapy can prolong the survival of the patients. For some patients with initially unresectable ICC, neoadjuvant therapy is an effective measure that may enable the patients to obtain the opportunity of radical surgical resection. |
| Key words: Intrahepatic cholangiocarcinoma(ICC) Surgical resection Lymphadenectomy |
