摘要: |
[摘要] 肝细胞癌(HCC)发病率高,乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染是HCC的主要病因。近年来,肥胖、2型糖尿病等代谢疾病的流行加速了非酒精性脂肪性肝病(NAFLD)的发生,导致NAFLD相关性HCC(NAFLD-HCC)的发生也逐年递增。但NAFLD-HCC与病毒相关性HCC是否有相似的发病机制、预防、监测以及治疗策略尚未清晰。该文就以上问题进行综述,为NAFLD-HCC的防治提供参考。 |
关键词: 肝细胞癌 非酒精性脂肪性肝病 治疗 总生存率 |
DOI:10.3969/j.issn.1674-3806.2022.02.03 |
分类号:R 735.7 |
基金项目:国家自然科学基金项目(编号:81960534) |
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Research progress in the treatment of non-alcoholic fatty liver disease-related hepatocellular carcinoma |
XIE Si, LI Le-qun
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Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning 530021, China
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Abstract: |
[Abstract] The incidence of hepatocellular carcinoma(HCC) is high, and hepatitis B virus(HBV) and hepatitis C virus(HCV) infections are the main causes of HCC. In recent years, the prevalence of metabolic diseases such as obesity and type 2 diabetes has accelerated the occurrence of non-alcoholic fatty liver disease(NAFLD), resulting in the occurrence of NAFLD-related HCC(NAFLD-HCC) increasing year by year. However, it remains unclear whether NAFLD-HCC and virus-related HCC have similar pathogenesis, prevention, surveillance and treatment strategies. This paper reviews the above problems and provides reference for the prevention and treatment of NAFLD-HCC. |
Key words: Hepatocellular carcinoma(HCC) Non-alcoholic fatty liver disease(NAFLD) Treatment Overall survival rate |