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头孢曲松钠联合左氧氟沙星治疗肝硬化并自发性细菌性腹膜炎的疗效观察
吴冬鸣
223002 江苏,淮安市第四人民医院肝病科
摘要:
[摘要] 目的 观察头孢曲松钠联合左氧氟沙星治疗肝硬化并自发性细菌性腹膜炎的疗效。方法 将72例肝硬化并发自发性细菌性腹膜炎随机分为治疗组37例和对照组35例,治疗组给予头孢曲松钠2 g,静脉注射,2次/d,左氧氟沙星注射液0.3 g,静滴,2次/d;对照组给予头孢哌酮/舒巴坦钠2 g,静滴,2次/d。疗程14~21 d,观察两组治疗后的疗效。结果 治疗组总有效率为89.19%,对照组总有效率为68.57%,治疗组疗效明显优于对照组(P<0.05)。结论 头孢曲松钠联合左氧氟沙星治疗肝硬化并自发性细菌性腹膜炎疗效显著。
关键词:  自发性细菌性腹膜炎  肝硬化  头孢曲松钠  左氧氟沙星
DOI:10.3969/j.issn.1674-3806.2011.11.15
分类号:R 575.2
基金项目:
Treatment of liver cirrhosis with spontaneous bacterial peritonitis by ceftriaxone sodium combined with levofloxacin
WU Dong-ming
Liver Section,the Fourth People′s Hospital of Huaian City,Jiangsu 223002,China
Abstract:
[Abstract] Objective To study the effects of the treatment of liver cirrhosis with spontaneous bacterial peritonitis by ceftriaxone combined with levofloxacin. Methods Seventy-two liver cirrhosis patients with spontaneous bacterial peritonitis were randomly divided into treatment group (37 patients) and control group (35 patients). The treatment group received ceftriaxone 2 g plus levofloxacin 0.3 g, the control group received cefoperazone/sulbactam 2 g intravenously two times, one per day.Patients were observed from 14 to 21 days after the treatment was administered. Results The total effective effect of the treatment group and the control group were 89.19% and 68.57% respectively.The efficiency of the treatment group was significantly higher than the control group ( P<0.05). Conclusion The ceftriaxone sodium combined with levofloxacin had a significant effect for the treatment of liver cirrhosis with spontaneous bacterial peritonitis.
Key words:  Spontaneous bacterial peritonitis  Liver cirrhosis  Ceftriaxone  Levofloxacin