| 摘要: |
| ［摘要］ 目的 观察自制持续气道正压通气（CPAP）装置用于单肺通气（OLV）对动脉血氧分压及肺内分流的影响。方法 40例择期肺叶切除术患者，ASAⅠ～Ⅱ级，随机分为CPAP组（A组）和肺萎陷组（B组），每组20例。A组单肺通气时在患侧肺使用自制CPAP装置给予5 cmH2O纯氧持续呼吸道正压通气，B组未予任何干预措施。分别于单肺通气前（T0）、单肺通气后30 min（T1）、单肺通气后60 min（T2）测定动脉及混合静脉血进行血气分析，并根据公式计算肺内分流率（Qs/Qt）。结果 两组T0时点PaO2相比较差异无统计学意义（P>0.05），T1、T2时点A组的PaO2均较B组高（P<0.01），而Qs/Qt两组间各时点对比差异均无统计学意义（P>0.05）。结论 单肺通气期间，在患侧肺使用该自制CPAP装置给予5 cmH2O CPAP,可增加动脉血氧分压，但对肺内分流无明显影响。 |
| 关键词: 单肺通气 持续气道正压通气 肺内分流 动脉氧分压 |
| DOI：10.3969/j.issn.1674-3806.2016.04.03 |
| 分类号:R 614 |
| 基金项目:广西卫计委科研课题（编号：桂卫Z2012318） |
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| Effects of self-made CPAP device on arterial oxygen pressure and intrapulmonary during one-lung ventilation |
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YU Mei-gang, HUANG Yu-ting, MO Yi-jie, et al.
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Department of Anesthesiology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To investigate the effects of self-made CPAP device on arterial oxygen pressure and intrapulmonary during one-lung ventilation(OLV).Methods 40 patients with ASA grade ⅠorⅡand a schedule for pulmonary lobectomy surgery and one-lung ventilation were randomly divided into 2 groups:CPAP group(group A, n=20) and matched group(Group B, n=20). In group A, CPAP in 5 cmH2O was administered to the non-ventilated lung by using the self-made device during OLV. Group B did not received any intervention during OLV. Arterial and mixed venous blood samples were taken for gas analysis before OLV(T1) and at 30 min(T2), 60 min(T3) after OLV. Intrapulmonary shunt(QS/QT) was calculated.Results There was no significant difference in PO2 between the two groups at T1(P>0.05). PaO2 in group A was higher than that in group B at T2 and T3(P<0.01). However, there were no significant differences in QS/QT between the two groups at T1, T2 and T3(P>0.05).Conclusion Using the self-made device to add 5 cmH2O CPAP can effectively improve arterial oxygenation during OLV, but does not affect the intrapulmonary shunt (Qs/Qt). |
| Key words: One lung ventilation（OLV） Continuous positive airway pressure（CPAP） Intrapulmonary shunt Arterial partial pressure of oxygen |
