| 摘要: |
| ［摘要］ 结直肠癌（CRC）是消化系统恶性肿瘤，起病隐匿，单靠症状和体征在临床上难以诊断，一旦确诊多数已经处于中晚期。CRC患者由于分期不同，预后有显著差异。CRC的早期筛查与诊断可以改善患者的生存情况，降低病死率。该文对粪便标志物、血液标志物和液体活体标志物检测诊断结直肠癌的研究进展进行综述。 |
| 关键词: 结直肠癌 标志物 液体活体标志物检测 炎症指标 |
| DOI：10.3969/j.issn.1674-3806.2023.08.20 |
| 分类号:R 735.3 |
| 基金项目:山东省自然科学基金项目（编号：ZR2020MH316，ZR2016HM52） |
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| Research progress in detection methods for diagnostic markers of colorectal cancer |
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ZHAO Shi-yu, BAO Guo-lin, FAN Wei-hua, et al.
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Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China
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| Abstract: |
| ［Abstract］ Colorectal cancer(CRC), as a malignant tumor of the digestive system, is difficult to diagnose clinically by symptoms and signs alone because of its insidious onset, and its symptoms and signs are usually in the middle and late stages when diagnosed. The prognoses of the patients with CRC are also significantly different due to different stages. Early screening and diagnosis of CRC can improve the survival of the patients and reduce their mortality. This paper reviews the research progress in the diagnosis of CRC through the detection of stool markers, blood markers and liquid biopsy. |
| Key words: Colorectal cancer(CRC) Markers Detection of liquid biopsy Inflammatory indicators |
