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干细胞在治疗急性心肌梗死中应用的研究进展
吕永波1，王　娟2
1.同济大学附属东方医院心内科，上海 200120；2.上海中医药大学附属龙华医院心病科，上海 200032
摘要:
［摘要］　急性心肌梗死是由各种原因（冠状动脉阻塞性或非阻塞性）导致的心脏血供急剧减少或中断，使相应心肌发生严重而持久的缺血，最终导致心肌细胞坏死。干细胞因具有多向分化、自我更新等特性，被用于心肌梗死后心肌的再生研究。该文对干细胞在治疗急性心肌梗死中应用的研究进展作一综述。
关键词:  干细胞  急性心肌梗死  心肌再生  心脏靶向
DOI：10.3969/j.issn.1674-3806.2024.09.21
分类号:R 541
基金项目:国家自然科学基金项目（编号：81271927）
Research progress on application of stem cells in treatment of acute myocardial infarction
LYU Yongbo1, WANG Juan2
1.Department of Cardiology, Shanghai East Hospital, Tongji University, Shanghai 200120, China; 2.Department of Heart Diseases, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Abstract:
［Abstract］　Acute myocardial infarction is a sudden reduction or interruption of blood supply to the heart due to a variety of obstructive or non-obstructive coronary causes, resulting in severe and persistent ischemia of the corresponding myocardia, ultimately leading to myocardial cell necrosis. Stem cells are used in the study on myocardial regeneration after myocardial infarction due to their multi-directional differentiation and self-renewal characteristics. In this paper, the research progress on application of stem cells in treatment of acute myocardial infarction is reviewed.
Key words:  Stem cell  Acute myocardial infarction(AMI)  Myocardial regeneration  Heart targeted