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《ISHAM-ABPA专家工作组对变应性支气管肺曲霉病/真菌病诊断、分类及治疗临床实践指南的修订》解读
周露茜1，冯添裕1，林志威1，王艳丽2，陈荣昌1，3，4
1.广州医科大学附属第一医院广州呼吸健康研究院，广东 510120；2.肇庆市中医院呼吸与危重症医学科，广东 526020；3.广州国家实验室深圳河套研究院，广东 510005；4.深圳市人民医院呼吸疾病研究所，广东 518109
摘要:
［摘要］　2024年，国际人类和动物真菌学会（ISHAM）的变应性支气管肺曲霉病（ABPA）专家工作组对2013年提出的ABPA诊断治疗指南进行了全面的修订。此次修订明确了变应性支气管肺曲霉病/真菌病的定义、检验检查、诊断标准、临床及影像学分型，并详细阐述了相应的治疗方法。新指南显著增强了变应性支气管肺曲霉病/真菌病诊断方面的敏感性，同时简化了其临床与影像学分型，使之更加易于理解和应用。新指南还根据临床分型提出了针对性的治疗原则，为临床医师提供了更为明确和实用的指导。该文就《ISHAM-ABPA专家工作组对变应性支气管肺曲霉病/真菌病诊断、分类及治疗临床实践指南的修订》进行深入解读，以期为相关领域的研究者和临床医师提供参考和借鉴。
关键词:  变应性支气管肺曲霉病  变应性支气管肺真菌病  指南解读
DOI：10.3969/j.issn.1674-3806.2024.12.01
分类号:
基金项目:国家重点研发计划项目（编号：2023YFF1203802）；广东省自然科学基金项目（编号：2023A1515012917，2024A1515012830）；广州医科大学科研提升项目（编号：2024SRP074)；高等教育教学改革项目（粤教高函【2024】9号-926）
Interpretation of Revised ISHAM-ABPA Working Group Clinical Practice Guidelines for Diagnosing, Classifying and Treating Allergic Bronchopulmonary Aspergillosis/Mycoses
ZHOU Luqian1, FENG Tianyu1, LIN Zhiwei1, WANG Yanli2, CHEN Rongchang1,3,4
1.Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangdong 510120, China; 2.Department of Respiratory and Critical Care Medicine, Zhao Qing Hospital of TCM, Guangdong 526020, China; 3.Guangzhou National Laboratory Shenzhen Hetao Research Institute, Guangdong 510005, China; 4.Respiratory Disease Institute, Shenzhen People′s Hospital, Guangdong 518109, China
Abstract:
［Abstract］　In 2024, the Allergic Bronchopulmonary Aspergillosis(ABPA) Working Group(AWG) of the International Society for Human and Animal Mycology(ISHAM) conducted a comprehensive revision of the diagnostic and therapeutic guidelines for ABPA proposed in 2013. This revision clarifies the definition, laboratory tests, diagnostic criteria, clinical and imaging classifications of ABPA/mycosis(M), and elaborates on the corresponding treatment methods. The new guidelines significantly improve the diagnostic sensitivity of ABPA/M and simplify the clinical and imaging classifications of ABPA/M, making the diagnosis of ABPA/M easier to understand and apply. The new guidelines also propose targeted treatment principles based on clinical classifications, providing more clear and practical guidance for clinicians. In this paper, Revised ISHAM-ABPA Working Group Clinical Practice Guidelines for Diagnosing, Classifying and Treating Allergic Bronchopulmonary Aspergillosis/Mycoses is interpreted in depth, aiming to provide reference and guidance for researchers and clinicians in related fields.
Key words:  Allergic bronchopulmonary aspergillosis(ABPA)  Allergic bronchopulmonary mycosis(ABPM)  Interpretation of guidelines