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自体富血小板血浆在呼吸系统疾病中的应用进展
李小鹏,黄 敏,袁守勤,何亚运,贺仁忠,江 湛
遵义医科大学附属医院呼吸与危重症医学科,遵义 563000
摘要:
[摘要] 富血小板血浆(PRP)富含高浓度血小板及多种生长因子,具有抗炎、促进细胞增殖及组织修复等性能。目前PRP已广泛应用在口腔科、骨科、整形科及耳鼻喉科等领域,疗效显著,安全性高。自体PRP来源于患者自身血浆,无免疫排斥反应及疾病传播风险。近年来,自体PRP逐渐应用于治疗支气管瘘、支气管出血、慢性阻塞性肺疾病、吸入性肺损伤和自发性气胸等呼吸系统疾病。该文对自体PRP在呼吸系统疾病中的应用进展作一综述。
关键词:  富血小板血浆  呼吸系统疾病  治疗  应用进展
DOI:10.3969/j.issn.1674-3806.2025.01.19
分类号:
基金项目:贵州省科学技术基金项目(编号:黔科合支撑[2021]一般437)
Progress in the application of autologous platelet-rich plasma in respiratory diseases
LI Xiaopeng, HUANG Min, YUAN Shouqin, HE Yayun, HE Renzhong, JIANG Zhan
Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China
Abstract:
[Abstract] Platelet-rich plasma(PRP) is rich in high concentrations of platelets and a variety of cytokines, and has the properties of anti-inflammatory, promoting cell proliferation and tissue repair. At present, PRP has been widely used in stomatology, orthopedics, plastic surgery, otolaryngology and other fields, with remarkable efficacy and high safety. Autologous PRP is derived from the patient′s own plasma without the risk of immune rejection and disease transmission. In recent years, autologous PRP has been gradually applied to the treatments of respiratory diseases such as bronchial fistula, bronchial hemorrhage, chronic obstructive pulmonary disease, inhalation lung injury and spontaneous pneumothorax. In this paper, the progress in the application of autologous PRP in respiratory diseases is reviewed.
Key words:  Platelet-rich plasma(PRP)  Respiratory diseases  Treatment  Application progress